Short peptides discovery could lead to new treatments for Alzheimer’s
The memory of mice with Alzheimer's greatly improved after they were injected with two newly discovered short peptides.
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New mechanism of controlling fat production revealed
A new study has shown a new mechanism of controlling fat production in the body which could lead to new therapies to treat obesity.
Mutant form of Ebola could be used in vaccine development
A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.
Researchers explain how lymphoma cells metastasise to the brain
Chronic inflammatory processes in ageing brains lead to lymphoma cells that have entered the brain tissue being retained.
Transplanted brain stem cells survive without anti-rejection drugs in mice
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.
Protein vital for enterovirus replication identified by study
Researchers have discovered a particular protein that is required for enterovirus replication and survival, presenting a therapeutic target.
Protein target for diabetes-related Alzheimer’s identified
A study has found a protein which, when depleted, resulted in Alzheimer’s disease symptoms appearing in mouse and brain tissue models.
Researchers improve CRISPR-Cas9 delivery efficiency
A team has used a lentiviral capsid-based bionanoparticle system to deliver CRISPR-Cas9 gene editing therapies, reducing undesired effects.
Role of gut microbiota studied in pregnant women with lupus
New research findings suggest that gut microbiota may regulate lupus flares in pregnant women, presenting a therapeutic target.
New strategy developed to speed up drug discovery process
A new drug discovery strategy predicts the clinical actions of new compounds to promote desired clinical responses and avoid side effects.
Drug target discovered for pulmonary arterial hypertension
Scientists have discovered a molecular pathway that contributes to PAH development, which may lead to a new drug target for the disease.
Study finds B cells could improve immunotherapies for cancer
Researchers have discovered that B cells aid T cells in fighting cancer, which could be an area of development for immunotherapies.
Treatment for polycystic kidney disease shows promising results
A potential treatment for polycystic kidney disease has shown positive results in animal testing.
Largest genome sequencing project launched in UK
The UK Biobank, the world’s largest genetics project, will sequence 500,000 genetic samples, which will be available to researchers everywhere.
Inflammatory regulator molecule identified by study
Researchers have discovered an enzyme that is pivotal in deciding whether cells survive or die in inflammatory diseases, so provides a drug target.