Direct toxic action of beta-amyloid in Alzheimer’s patients identified
The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.
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Four cell types discovered in glioblastoma tumours
A new study has revealed that glioblastomas contain four different types of cell which the researchers say should be treated separately.
Experimental compound could be used to treat pancreatic cancer
Using a compound called PTC596 in combination with other drugs, researchers effectively treated pancreatic cancer in mice.
Therapeutic target for Kennedy’s disease and prostate cancer proposed
A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.
Potential treatment target identified for Crohn’s disease
Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.
Interferon pathway could provide drug target for cancers
A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.
CRISPR-Cas used to edit cystic fibrosis gene mutations
A research team have used genome editing to correct two of the mutations that cause cystic fibrosis.
Industry objects to unproven T-cell preservation services
The ISCT is objecting linking the benefits of cellular immunotherapy with third party offerings of T-cell banking for future therapeutics.
Novel nano-vaccine for melanoma developed
A novel nano-vaccine has been developed which has proven effective in treating primary tumours and metastases that result from melanoma.
New drug could be used for targeted cancer therapies
A new drug called IP1867B, which could be used for future treatments of brain tumours, is being examined.
Researchers grow genetically engineered mini livers to study disease
The first genetically modified mini human livers have been grown in a laboratory, to emulate liver disease progression and test therapeutics.
Human stem cell combination could help damaged hearts live longer
A combination of heart cells derived from human stem cells could lead to developing a treatment for heart failure.
New model predicts cognitive decline two years ahead
Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.
New model can help translate mice research into human health results
A new mouse model, called 'wildlings', has been developed which better mirrors human immune responses than standard laboratory mice.
Experimental treatment slows prion disease
A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice