Protective protein guards against DNA damage
It has been discovered that Polo-like kinase (PLK1) guards against severe DNA damage and could help target fast-growing cancer cells.
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Allergy-driving cells identified as potential drug targets
Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.
Study reveals cancer cell fuelling mechanism
Researchers have identified the process behind cancer cell energy production, providing a drug target for treatments to inhibit growth.
Molecular Devices introduces the FLIPR® Penta system
Molecular Devices, LLC, today announced the launch of the next generation of its FLIPR® Penta High-Throughput Cellular Screening System.
OX40-expressing follicular helper T cells can control rheumatoid arthritis
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.
Antibody therapy extends survival in mice with pancreatic cancer
Scientists have found a way to target and knock out a protein which is widely involved in pancreatic cancer cell growth, survival and invasion.
Cancer cell nutrient pathway mechanism discovered
Researchers have discovered the mechanism behind a gateway into cells for glutamine, illuminating potential ways to prevent cancer cells from getting nutrients.
Motor neuron disease electrical signalling pathways mapped
A study has used EEG to investigate the neuron networks that act abnormally in the condition, providing a significant step in the search for treatments.
Targeting a blood stem cell subset shows lasting gene editing
Scientists report how editing a portion of stem cells with CRISPR-Cas9 is sufficient for long-term reactivation of therapeutic haemoglobin.
Newly discovered signal could lead to anti-cancer therapies
Researchers have newly found that protein CD24 acts as a defensive signal and is used by cancer cells to protect themselves.
Researchers discover new neuroblastoma drug target
A study has discovered that reducing expression of a key gene in neuroblastoma tumourigenesis is an important drug target for the condition.
Study of TP53 mutations shows insight into the gene’s function
New study sheds light on how the TP53 gene becomes mutated and how those mutations can help predict clinical outlooks for cancer.
New therapy discovered to treat acute lymphoblastic leukaemia
Researchers have discovered a new combination therapy to treat drug-resistant acute lymphoblastic leukaemia, tested in pre-clinical trials.
Study identifies potential drug target for prostate cancer
Researchers have discovered a non-coding RNA which could be used as a biomarker and in new therapies for prostate cancer.
New discovery could lead to new treatments for Parkinson’s
New discovery makes it possible to design new therapies to replace alpha-synuclein's function in people with Parkinson's disease.