Using anti-malaria drugs to slow tumour growth
Anti-malaria drugs, called chloroquines, target PPT1 from cancer cells, with researchers identifying how the drugs eliminate tumour growth in cancers...
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Spined soldier bug can be used to develop new classes of antibiotics
Researchers have identified the mechanism by which thanatin attacks the way the outer membrane of Gram-negative bacteria is built...
Precision neuroengineering reproduces brain-like functions in vitro
Using precision engineering, researchers form Japan and Spain have collaborated to show brain-like functions in vitro to advance medical research...
Advanced biomaterial improves stem cell therapy for strokes
Researchers in Spain have achieved functional recovery from a stroke after implanting silk fibroin hydrogels-encapsulated stem cells in stroke mice.
Immune cell enzyme protects against tuberculosis
Using lung tissue from humans and mouse models, researchers have found that HO-1 controls inflammation and protects against tuberculosis...
Combination of imaging techniques views retina in unprecedented detail
Using two imaging techniques, adaptive optics and angiography, researchers have been able to view the retina in more detail than ever seen before...
Inhibiting USP13 destroys toxic clumps seen in Parkinson’s disease
A team of neurologists have found that one reason Lewy bodies develop is that a molecule, USP13, has removed all the "tags" placed on alpha-synuclein that mark the protein for destruction...
Defective damage repair to DNA results in chromosome chaos
German researchers have shown how defective damage repair to DNA results in chromothripsis - clustered chromosomal rearrangements...
Vaccinia virus hijacks cellular movements to spread
To spread throughout the body, the vaccinia virus mimics the infected cells' own proteins enabling the cell to move around and spread...
CRISPR used to prevent cancers tied to EBV and KSHV
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...
RIP1 kinase as a therapeutic target for pancreatic cancer
RIP1 has been shown to suppress the action of macrophages against the immune system and could be a potential therapeutic target for pancreatic cancer...
Swarm of exosomes protect against inhaled bacteria
A swarm of billions of exosomes armed with proteins has been shown to assist in the fight against bacteria inhaled through the nose...
Mouse model for diabetic kidney disease suggests role for immune and inflammatory pathways
Scientists have designed mice that successfully emulate a severe form of kidney damage in humans with diabetes, called diabetic nephropathy...
Scientists test new anti-PD-L1 cancer vaccine against melanoma
An experimental cancer vaccine that boosts the immune system's ability to fight cancers could work in tandem with other cancer therapies to fight aggressive tumours, scientists have reported...
Magnetically controlled thrombolytic passed preclinical trials
ITMO University scientists have used nanoparticles and magnetic waves to localise drug delivery in animal models, resulting in no side effects...