New AI model can evaluate invasive breast cancer outcomes
Combining cancerous and non-cancerous cell patterns, the AI model evaluates breast cancer outcomes better than expert pathologists.
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New contamination-detection test to improve T-cell therapy
Method to improve sterility assurance in biopharmaceutic manufacturing will lead to better patient outcomes.
Mitochondria-targeting antibiotics reduce aging in C. elegans
Treating C. elegans with inhibitors of small or large mitochondrial ribosomes extended their median lifespan.
Y chromosome discovery could advance personalised medicine
Researchers have completely decoded the human Y chromosome, which may result in more effective treatment for digestive disorders.
New algorithm identifies a novel CRISPR-Cas system
Findings of rare CRISPR-linked gene modules and a novel CRISPR-Cas system have promising implications for genomic therapeutics.
Potential of small molecule therapeutics for Barth syndrome
Novel findings about the tafazzin gene offers a potential new target and drug candidate for Barth syndrome.
Noncoding RNA could be a new target for acute myeloid leukaemia
Discovery about the DNA of leukaemia cells suggests promising target for gene therapy in paediatric oncology.
Genetically engineered transplants avoid immune rejection
Researchers have found a way to genetically modify stem cells so that cell and organ transplants are not rejected.
Target found for pulmonary hypertension treatment
An epigenetic pathway is mediated by a certain protein that could potentially reverse vascular remodelling in pulmonary hypertension.
Engineered biofilm helps to tackle infections in CF patients
A living material resembling sputum from CF patients can grow biofilms, enabling scientists to assess the effectiveness of antimicrobials.
Nano-sized traps enable better study of proteins
Researchers have developed a new method to study protein clumps that occur in many difficult-to-treat diseases.
New colon organoids better resemble both healthy and diseased colons
Researchers have developed organoids with naturally occurring early-stage immune cells, which could lead to effective personalised treatment.
Improving treatment response to KRAS inhibitors
Eliminating AT1-like cells in experimental models has shown potential to improve KRAS inhibitor treatment for lung adenocarcinoma.
Promising strategy for glaucoma cell replacement therapy
Changing blood stem cells into retinal ganglion cells that can migrate to the eye’s retina offers hope for cell replacement therapy.
Ribosomes repair damage to single stranded RNA
Crosslinking damage to single stranded RNA, caused by aldehydes, is repaired by newly discovered mechanism involving ribosomes.