Drug target identified in oestrogen receptors
A bridge-like structure in oestrogen has been identified by researchers at Case Western Reserve University School of Medicine as a potential drug target...
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Rutin could be effective in treating snakebites from pit vipers
The action of a venomous snakebite from vipers could be treated using a flavonoid called rutin, an inexpensive plant based compound...
Vaccine offers complete protection against Ebola virus
Researchers at The Wistar Institute have developed a DNA based vaccine that has offered compete protection against the Ebola virus in preclinical trials...
Immunotherapy could cure advanced pancreatic cancer
Immunotherapy using 'educated' killer cells could be a potential cure for pancreatic cancer, with researchers eliminating all signs of cancer from mice...
PIEZO2, a molecular target for neuropathic pain
Scientists at Scripps Research have identified the molecule in neurons responsible for tactile allodynia, a protein called PIEZO2...
Early treatment could reverse autistic behaviour in tuberous sclerosis
Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
Micropeptide molecule restores heart function
A micropeptide molecule that reverses structural and functional changes in the heart could be a promising target for gene therapy...
Scientists find treatment for tumour cell population that causes tumour relapse
Researchers in Europe have developed a treatment that targets a tumour cell population responsible for therapy resistance and tumour relapse, giving optimism for patients with the most frequent form of cancer.
Could gene mutation offer new treatment options for cardiometabolic disease?
Researchers in the states have discovered a particular gene mutation that slows down sugar metabolism in the gut, indicating future treatment options for individuals with cardiometabolic and sugar-associated diseases.
CRISPR technique identifies Alzheimer’s biomarker
UEx researchers have identified a potential biomarker for Alzheimer's disease using the CRISPR gene editing technique to analyse brain samples...
Elrig 2018: Drug discovery using small and large molecules
The Drug Target Review team are at Elrig Drug Discovery 2018 in the London ExCel...
Prenatal gene editing used in treating congenital disease before birth
Researchers show the first example of a base-editing tool to treat a disease in utero in animal models...
Biodegradable devices speed up nerve regeneration
Researchers have developed an implantable and biodegradable device to aid the regeneration of nerve after damage from accidents and sports injuries...
Scientists create map of brain region linked to Alzheimer’s disease
Scientists have mapped areas of the brain that are linked to Alzheimer's disease to deliver genetically-targeted drugs to specific neurons...
Efficacy of PET imaging in managing chronic liver diseases
PET imaging could be used as a non-invasive substitute to painful and complicated liver biopsies for chronic liver disease...