Scientists pinpoint mechanism by which mutant p53 protein promotes cancer
Scientists in Australia have discovered how the most important gene in preventing cancer, TP53, is hampered in its tumour-fighting efforts by mutant p53 proteins.
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Making old antibiotics work better using r8
A team of researchers have developed a way that could enhance the effect of current antibiotics, using a small molecular attachment called r8...
P2K system could resolve bottlenecks in drug research
Researchers have developed a new system that could significantly speed up the discovery of new drugs and reduce the need for costly and time-consuming laboratory tests...
Parasitic worm study predicts potential drug targets and drugs
The largest ever parasitic worm study has revealed nearly 1 million new genes, and has identified potential drug targets and drugs...
Potential of gene therapy for neurological disorders
Gene therapy could be effective in numerous neurological conditions and could transform the lives of patients with these incurable diseases...
NGLY1 protein identified as potential target for melanoma treatment
Scientists in the United States have inadvertently uncovered a promising treatment for melanoma that targets the NGLY1 gene.
Tethered antibodies may prevent influenza virus infections
Investigational therapeutic candidate made with four antibodies tethered together shows promise against influenza A and B...
Stem cell therapy with biodegradable scaffold
A biodegradable scaffold used to transplant stem cells and deliver drugs, could help in the treatment of brain diseases...
Heat-resistant enzymes for cost-effective drugs
The mechanisms and actions of heat-resistant enzymes are being investigated to aid better, more cost-effective drug design...
Charles River to present collaborative methods at Neuroscience 2018
Charles River Laboratories International, Inc. (NYSE: CRL) announced that its team of neuroscience drug discovery experts will present 26 scientific posters, both independently and collaboratively with clients, at Neuroscience 2018, the 48th annual meeting of the Society for Neuroscience (SfN)...
Charles River and Distributed Bio enter exclusive partnership to create an integrated antibody discovery and development platform
Charles River Laboratories International, Inc. announced that it has entered into an exclusive partnership with Distributed Bio, Inc., a leader in the computational design and optimisation of antibody discovery platforms...
Biomarkers may predict Zika-related birth defects
Researchers have identified biomarkers associated with severe birth defects in babies born to women infected with the Zika virus...
Image of serotonin activating its receptor for the first time
Researchers have managed to image serotonin activating its receptor for the first time using the cutting edge technology, cryo-electron microscopy...
MDM2 inhibitors as a possible treatment for uveitis
MDM2 inhibitors could be used as a treatment for uveitis, a disease affecting the middle layer of the eye, causing inflammation and redness...
New Cas9 enzyme widens scope for CRISPR genome editing
A team of researchers has discovered a Cas9 enzyme that can target almost half of the locations on the genome, significantly widening its potential application.