Cryo-EM shows structure of TRPM2
The structure of the protein TRPM2, a possible drug target, has been revealed for the first time by researchers at Van Andel Research Institute...
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Breast tissue simulations address enhanced MRI delays
Researchers address the delay of enhanced MRI cancer detection using simulations of women's breast tissue and higher MRI strengths...
Scientists report using pluripotent stem cells to grow human oesophagal organoids
Scientists have been able to grow human oesophagal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body...
Mitochondrial diseases could be treated with gene therapy
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
Protein ‘trafficker’ provides insight into autism
The protein ASTN2 has been identified as a trafficking protein that ushers proteins away from the membrane ready for degradation in the cell...
Nanotherapy offers hope in treating drug-resistant renal cell carcinoma
A research team has developed a nano-platform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma...
Cancer cells hide to evade immunotherapy
Cancer cells have been found to evade immunotherapy by hiding behind human leukocyte antigens, with researchers identifying therapies to prevent relapse...
A universal flu vaccine may be in sight
Researchers from Oxford have identified the initial steps on the path towards creating a universal influenza vaccine that could last for life...
Laser-capture RNA seq technique connects Parkinson’s and psychiatric diseases
A comprehensive study reveals an expanding universe of 'darkest of the dark matter' RNAs in dopamine-producing cells in our brains...
Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...
PD-1 and CTLA4 therapies together could benefit women with ovarian cancer
Women with ovarian cancer could in future benefit from a combined therapy using PD-1 and CTLA-4 as shown through the results of this Phase II trial...
Detecting epigenetic signature may help people stay ahead of IBD
Researchers have reported finding on an epigenetic signature in patient cells that appears to predict inflammation risk in Crohn's disease...
NLRP12 protein promotes healthy gut bacteria to curb obesity
Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet...
Green tea compound helps siRNA slip inside cells
Researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells...
Amyloid beta – a good therapeutic target?
Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...