Estradiol exerts anticancer effects in triple-negative breast cancer
Researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer...
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Nonresponsive NK cells directly impact malaria severity
The failure of natural killer cells (NK cells) to respond to infection explains why malaria causes a worse reaction in some patients than others.
RNA-seq of 20,000 cardiac cells reveals heart disease insights
RNA analysis of 20,000 cardiac cells from heart tissue in both ordinary and deceased mice showed an insight to the development of heart disease...
Chemotherapy and APOE4 linked to cognitive issues
Both human and mouse models show that chemotherapy and APOE4 are linked to cognitive issues faced by patients who overcome cancer...
Nuclear tracer helps to study the aging brain
A PET nuclear tracer could help researchers to understand neurodegeneration in aging brains better, as it enters the brain and distributes quickly...
SERDs molecules could spur a new class of drugs for breast cancer
Stevens researchers design and develop a new class of molecules for breast cancer therapy...
Algorithm to more effectively identify antibiotic compounds
An international team of scientists has developed a candidate identification technique in the form of an algorithm that reduces the chances of rediscovering known compounds.
Umbilical cord stem cells used for early repair of cleft palate
Stem cells harvested from the umbilical cord after birth could lead to a therapy to treat cleft lip and palate without the traditional surgery...
Alpaca immune system reveals a potential treatment for cancer
Researchers have identified camelid nanobodies that are able to block EGF, a protein that is abundant in tumour cells...
Cancer immunotherapy researchers win Nobel prize
Researchers from the US and Japan have received the Nobel prize in medicine for their development of cancer immunotherapy using PD-1 and CTLA-4...
PSD-95 molecule reveal potential treatment for stroke patients
A novel hybrid approach has revealed a 3D structure of a protein fragment that could serve as a drug target in treating stroke patients...
Rare mechanism for ALL to relapse after CAR-T therapy
A single leukemic cell has become resistant to CAR-T therapy after unknowingly engineered with the leukemia-targeting CAR lentivirus...
Targets for chronic kidney disease treatment
The DAB2 pathway could be a crucial target in treating CKD, as mouse models show a decrease in DAB2 leads to prevention of the condition...
New technique generates brain stem cells more efficiently
Scientists in Ohio have developed a more efficient means of creating brain stem cells, specifically oligodendrocyte progenitor cells, or OPCs, which will help facilitate greater understanding of neurological disorders that result from myelin damage.
Oxygen sensitive nanoparticles used for 3D printing of complex tissue-like structures
Researchers have implemented oxygen sensitive nanoparticles into a gel material that can be used for 3D printing of complex, biofilm and tissue-like structures...