Mitochondrial diseases could be treated with gene therapy
Researchers have developed a genome-editing tool for the potential treatment of mitochondrial diseases...
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Protein ‘trafficker’ provides insight into autism
The protein ASTN2 has been identified as a trafficking protein that ushers proteins away from the membrane ready for degradation in the cell...
Nanotherapy offers hope in treating drug-resistant renal cell carcinoma
A research team has developed a nano-platform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma...
Cancer cells hide to evade immunotherapy
Cancer cells have been found to evade immunotherapy by hiding behind human leukocyte antigens, with researchers identifying therapies to prevent relapse...
A universal flu vaccine may be in sight
Researchers from Oxford have identified the initial steps on the path towards creating a universal influenza vaccine that could last for life...
Laser-capture RNA seq technique connects Parkinson’s and psychiatric diseases
A comprehensive study reveals an expanding universe of 'darkest of the dark matter' RNAs in dopamine-producing cells in our brains...
Promising new vaccine developed for vivax malaria
A study indicates the possibility of using tiny vesicles derived from human immature red blood cell as a vaccine platform...
PD-1 and CTLA4 therapies together could benefit women with ovarian cancer
Women with ovarian cancer could in future benefit from a combined therapy using PD-1 and CTLA-4 as shown through the results of this Phase II trial...
Detecting epigenetic signature may help people stay ahead of IBD
Researchers have reported finding on an epigenetic signature in patient cells that appears to predict inflammation risk in Crohn's disease...
NLRP12 protein promotes healthy gut bacteria to curb obesity
Scientists have discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet...
Green tea compound helps siRNA slip inside cells
Researchers have found a surprising use for EGCG: sneaking therapeutic RNAs into cells...
Amyloid beta – a good therapeutic target?
Phase III clinical trials for a drug targeting amyloid beta plaques are underway, with results expected in the next two to three years...
ELRIG UK Drug Discovery 2018 Event
ELRIG’s (European Laboratory Research & Innovation Group) Drug Discovery meeting, will take place at ExCeL, London, UK, located in the heart of the city, from 9 -10 October 2018...
New understanding of T-cell receptor behaviour presents challenge for immunotherapies
Researchers in the U.S. have made a surprising discovery about the binding behaviour of a particular T-cell receptor, with complicated ramifications for immunotherapy developers.
Np63a should be targeted in squamous cell carcinomas
A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...