New assay to detect genetic abnormalities in sarcomas
A new study describes an assay, anchored multiplex PCR (AMP)-based targeted next-generation-sequencing (NGS), with superior diagnostic utility compared to conventional techniques...
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Modified-RNA vaccine elicits protective response against influenza
A universal flu vaccine that protects people against most influenza strains is one step closer to reality...
Blood test may identify cancer patients who won’t respond to immunotherapy
Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test...
Researchers develop biosensor with real-time oxygen monitoring
In a study, researchers have developed a biosensor concept using organs-on-a-chip to measure the levels of oxygen in real-time...
Vitamin B3 could potentially treat kidney injury
A team of researchers have identified vitamin B3 can increase levels of NAD+, which is decreased in those with acute kidney injury...
Research team develops predictor for immunotherapy response in melanoma
Researchers have developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors...
Cocaine relapse is reversed with BDNF microinjections in the brain
Researchers have discovered that a very common protein in the brain has an additional significant role in addiction relapse...
Compound with selectivity for cancer cells without p53 identified
The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...
GC4419 could prevent debilitating side effect of cancer treatment
Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
Mouse models’ mimic lung disease
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
CRISPR technique skips over portions of genes that can cause disease
Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
Anticancer drug as an alternative to liver transplant
Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
Chemical that can kill glioblastoma cells identified
"As an experimental chemical, further rigorous testing and refinement of KHS101 is required before trials in people can begin.”
RUNX proteins essential for DNA repair
The research team identified that the more the DNA was damaged, the more RUNX proteins bound to DNA repair intermediaries...
New lead for Alzheimer’s research proposed
Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...