Matcha green tea kills cancer stem cells 31 August 2018 | By Iqra Farooq (Drug Target Review) Researchers have found that Matcha green tea has properties to combat breast cancer stem cells...
Inhibiting NF-κB improves heart function in Duchenne muscular dystrophy 31 August 2018 | By Drug Target Review Breakthrough research has uncovered an unexpected mechanism that underlies cardiomyopathy in DMD...
Dectin-1 pathway may be crucial for treating fungal inflammation and pain 30 August 2018 | By Iqra Farooq (Drug Target Review) Researchers have identified the dectin-1 pathway as being a potential target for the treatment of pain associated with candidiasis...
Scientists discover compound for a non-addictive painkiller 30 August 2018 | By Iqra Farooq (Drug Target Review) Scientists have discovered the chemical compound AT-121, which could soon lead to a painkiller stronger than morphine, but without the side effects...
Potential drug to cure ciliopathies 30 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a potential treatment that will be a foundation for developing drugs for various genetic disorders...
TLR5 protein holds potential for new Alzheimer’s biotherapy 29 August 2018 | By Drug Target Review Researchers at the University of Florida have discovered that a modified version of an important immune cell protein, TLR5, could be used to treat Alzheimer's disease.
Discovery of markers that predict evolution of triple-negative breast cancer 29 August 2018 | By Drug Target Review Researchers in Spain have identified a means of classifying patients with the most aggressive form of breast cancer - triple negative breast cancer; providing meaningful prognosis for the first time.
Scientists develop TSA-Seq technique for precise 3D mapping of human genome 29 August 2018 | By Drug Target Review Despite the human genome being first sequenced almost 20 years ago, researchers know comparatively little about how the genome is organised within cells. But a new TSA-Seq technique is changing that.
NF-2 gene mutations make cells hyper-responsive to growth factor signalling 29 August 2018 | By Drug Target Review Researchers have determined one way that mutations in a gene involved in a rare, hereditary cancer syndrome lead to out-of-control cellular proliferation...
Novel imaging biomarker to help predict coronary inflammation 29 August 2018 | By Drug Target Review Researchers have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality...
Brain-heart link points at potential biomarker for trauma-induced epilepsy 28 August 2018 | By Drug Target Review Scientists at Penn State find that heartbeat irregularities connected to brain activity abnormalities may pave the way to predict onset of epilepsy in certain patients…
Scientists show combined immunotherapy treatment is effective against advanced melanoma 28 August 2018 | By Drug Target Review Study in the U.S. demonstrates successful treatment of advanced melanoma and metastatic cancer using a new bacteria-like agent combined with an immunotherapy drug.
The molecular link between ageing and neurodegeneration 28 August 2018 | By Drug Target Review Researchers have described the discovery of a molecular link between ageing and a major genetic cause of both ALS and FTD...
NanoMIPs efficiently target and eliminate cancer cells 24 August 2018 | By Dr Zara Kassam (Drug Target Review) A joint research team has demonstrated the possibility of developing a new type of anti-neoplastic drugs based on nanoMIPs...
Powerful molecules provide new findings about Huntington’s disease 23 August 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease...