Researchers develop biosensor with real-time oxygen monitoring
In a study, researchers have developed a biosensor concept using organs-on-a-chip to measure the levels of oxygen in real-time...
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Vitamin B3 could potentially treat kidney injury
A team of researchers have identified vitamin B3 can increase levels of NAD+, which is decreased in those with acute kidney injury...
Research team develops predictor for immunotherapy response in melanoma
Researchers have developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors...
Cocaine relapse is reversed with BDNF microinjections in the brain
Researchers have discovered that a very common protein in the brain has an additional significant role in addiction relapse...
Compound with selectivity for cancer cells without p53 identified
The compound has been shown to target cancer cells without the p53 gene, and does not affect healthy cells...
GC4419 could prevent debilitating side effect of cancer treatment
Researchers are reporting on a new drug that can treat the painful and debilitating side effect of severe oral mucositis (SOM)...
Mouse models’ mimic lung disease
Researchers have finally been able to mimic IPF in mouse models - a debilitating disease, with no proper treatment and no cure...
CRISPR technique skips over portions of genes that can cause disease
Researchers have adapted CRISPR to cause the cell's internal machinery to skip over a small portion of a gene when transcribing it into a template for protein building...
Anticancer drug as an alternative to liver transplant
Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...
Chemical that can kill glioblastoma cells identified
"As an experimental chemical, further rigorous testing and refinement of KHS101 is required before trials in people can begin.”
RUNX proteins essential for DNA repair
The research team identified that the more the DNA was damaged, the more RUNX proteins bound to DNA repair intermediaries...
New lead for Alzheimer’s research proposed
Researchers identified a connection between the way neurons handle iron and mutations that may cause inherited Alzheimer's disease...
Effective approach to optimising medicinal molecules
Computational methods accelerates and automates the process of optimisation of candidate molecules before performing preclinical trials...
IgG3 antibody can block B cells from fighting pathogens during HIV infection
Scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens...
Targeting the growth signals of ‘undruggable’ cancers
Dr Bivona and his team showed that the growth of multiple cancers slowed by suppressing the signalling pathway using an experimental compound...