D-PDMP reverses hair loss and skin damage linked to fatty diet
In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...
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Computer simulations predict the spread of HIV
Genetic signatures trace the origin of infection and its potential path through populations, allowing state health departments to track the disease...
Is acidity the weakness of cancer cells?
Cancer cells proliferating in alkalinity should be more vulnerable in acidic environments, so decreasing the pH may result in decreased proliferation...
Monoclonal antibodies produced by new cell lines hope to improve drugs
Many biopharmaceutical companies look to produce biosimilars soon, since the patents on the original mAb expire over the next few years...
AI system designs drugs from scratch
An artificial-intelligence approach created can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates...
Research into cellular signalling mechanisms may lead to new treatments
Wnt moves to specific areas of the cell membrane, interacting with a receptor known as Ror2, and inducing the formation of a cytoneme...
Novel antibiotics can be found on common weeds
The team studied chemical compositions in detail and from one strain of bacteria several antibiotically active chemical substances were discovered...
IKZF1 gene could improve cancer immunotherapy
A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy...
CBD improves survival rates of mice with pancreatic cancer
Mice with pancreatic cancer that were treated with CBD alongside chemotherapy, survived almost three times longer than those treated with chemotherapy alone...
Susceptible genes for childhood nephrotic syndrome identified
A specific haplotype was identified as having the highest risk of development, with another showing the lowest risk...
New ligand binding site identified through computer simulations
Many therapeutic compounds target GPCRs and so new ligand binding sites can help to design drugs more efficient at targeting GPCR...
CMPK2 inhibitor could lesson symptoms of common illnesses
CMPK2 inhibitors may reduce inflammation, pain and tissue damage in arthritis and gout and in Alzheimer’s may slow loss of cognitive function...
UBR5 protein may reduce neurodegeneration in Huntington’s disease
Scientists have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease...
New drug for ALS ready for clinical trials
Previous studies have suggested that a gene therapy drug may be used to treat ALS...
BCX7353 shows hope for hereditary angioedema
A new drug has been developed to help prevent attacks of hereditary angioedema and at the same offer patients a convenient administration...