New insight into Huntington’s disease may open door to drug development
Researchers have developed a new theory on Huntington's disease which is being welcomed for showing promise to open new avenues of drug development for the condition...
List view / Grid view
News
PNA gene editing technique cures beta-thalassemia in utero
Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model...
New targets found to reduce blood vessel damage in diabetes
Researchers identify new treatment targets for diseases associated with endothelial cell senescence, or ageing, such as diabetes, cardiovascular disease and age-related disorders...
How does Parkinson’s disease develop?
Study raises doubts on a previous theory of Parkinson’s disease...
New software designed for rapid, automated identification of dendritic spines
Researchers release open source software, connecting and building the neuroscience coding community...
CRISPRa used to reprogramme skin cells into pluripotent stem cells
Researchers have now for the first time succeeded in converting skin cells into pluripotent stem cells by activating the cell's own genes...
Experimental drug stops Parkinson’s disease progression in mice
Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...
Algorithm used to map cancer resistance to drugs
New methods of studying the evolution of treatment resistance in head and neck cancer are being developed by researchers at the Johns Hopkins Kimmel Cancer Center...
Stem cells restore function in primate heart-failure study
Results suggest an approach that could be tested for treating people with heart failure...
Next-generation therapeutic helps immune cells detect, destroy cancer
Researchers have found that cancer cells evade destruction by macrophages in two ways...
CRISPR technology can correct Alpha-1 antitrypsin deficiency
Groundbreaking research demonstrates proof-of-concept for using CRISPR-Cas9 genome editing technology to correct the gene mutation responsible for AAT deficiency...
Novel drug therapy partially restores hearing in mice
A small-molecule drug is one of the first to preserve hearing in a mouse model of an inherited form of progressive human deafness, report investigators at the University of Iowa, Iowa City, and the National Institutes of Health’s National Institute on Deafness and Other Communication Disorders (NIDCD).
Administering hormones affects DNA
In an experiment with pigs, researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor - in this case, an endogenous oestrogen - leads to epigenetic changes in a pregnant sow’s DNA.
New cancer immunotherapy shows promise in early tests
Researchers report that in preclinical models they can amplify macrophage immune responses against cancer using a self-assembling supramolecule...
New biomarker provides personalised treatment options for bladder cancer
Researchers use data science and genomics to help determine best treatment options for specific bladder cancers...