CRISPR-Cas9 tool could increase cancer risk
Therapeutic use of gene editing with the so-called CRISPR-Cas9 technique may inadvertently increase the risk of cancer...
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ANT1 mutation links bipolar disorder to mitochondrial disease
Researchers have reported that mitochondrial dysfunction affects the activity of serotonergic neurons in mice with mutations of ANT1...
p53 gene prevents cancer development
Scientists have discovered how the most important gene in preventing human cancer, p53, is able to stop the development of lymphoma and potentially other types of cancer...
Eosinophilic esophagitis may be due to missing SPINK7 protein
NIH-funded study finds replacement therapy reversed effects in tissue experiments...
Link found between neurotransmitter imbalance and brain connectivity in those with autism
Researchers have identified a link between a neurotransmitter imbalance and brain connectivity between regions of the brain that play a role in social communication and language.
Collaborative team first to identify the perinexus in the human heart
A collaborative research team is on a quest to collapse a tiny pocket between cardiac cells, called the perinexus.
E06 antibody blocks inflammation from hardened arteries and liver disease
Study uncovers new potential therapeutic approach for a number of diseases linked to inflammation, including atherosclerosis, aortic stenosis and hepatic steatosis...
ISSCR 2018 to highlight research driving new discoveries and advances in regenerative medicine
Progress in stem cell research and its translation to medicine is the focus of the International Society for Stem Cell Research annual meeting 20-23 June at the Melbourne Convention & Exhibition Centre in Melbourne, Australia.
SMCHD1 protein found essential to X chromosome inactivation
The structural protein is required for the chromosome to adopt a conformation that suppresses gene expression...
Scientists decode ASCT2 protein as possible cancer drug target
Scientists in the Netherlands have investigated the structure of the human glutamine transporter ASCT2 in a bid to generate leads for cancer drug development.
Scientists create ‘genetic atlas’ of proteins in human blood
Researchers have created the first detailed genetic map of human proteins...
ImmunoPET imaging noninvasively pinpoints colitis inflammation
A novel PET imaging method shows promise for noninvasively pinpointing sites of inflammation in people with inflammatory bowel disease...
Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.
Novel gene in red blood cells may help adult newts regenerate limbs
Japan-US research collaboration has found that red blood cells that express a novel gene may contribute to adult newt limb regeneration.
Scientists link inflammatory signalling to atrial fibrillation
An international team of scientists have found that interfering with inflammatory signals produced by heart muscle cells might someday provide novel therapeutic strategies for atrial fibrillation.