Profiling the genome hundreds of variations at a time
A CRISPR-Cas9 high-throughput strategy creates the possibility to rapidly profile and identify genes and DNA sequence variations key to different traits and diseases.
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Scientists reveal model that estimates lifetime risk of developing Alzheimer’s dementia
The Alzheimer’s Association have published a study wherein a model estimates the lifetime risk of an individual developing Alzheimer’s disease dementia. The risk varies with such factors as age and gender, and crucially takes account of preclinical biological changes.
Link between TB and Parkinson’s disease identified
The mechanism our immune cells use to clear bacterial infections like tuberculosis might also be implicated in Parkinson's disease...
Cell types underlying schizophrenia identified
Scientists have identified the cell types underlying schizophrenia, the findings offer a roadmap for the development of new therapies to target the condition...
Bladder cancer model could pave the way for better drug efficacy studies
Researchers have created a tool that may help them to uncover why only a fraction of patients responds to new immune-based treatments...
Blood test rapidly detects signs of pancreatic cancer
A new diagnostic test developed by researchers at UC San Diego shows promise for detecting pancreatic cancer earlier...
CHRNA2 receptor proteins may help fat cells burn energy
The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells...
Macrophages support mammary stem cells via chemical signalling
An international team of scientists has discovered that one of the biggest hitters in the immune system, macrophages, provide a cradle for mammary stem cells...
CRISPR used to destroy the regulatory genes of HIV
By destroying the regulatory genes of the AIDS virus HIV-1 using the genome editing system CRISPR/Cas9, researchers have succeeded in blocking the production of HIV-1 by infected cells...
NMT molecule provides hope for common cold cure
Researchers have lab-tested a molecule that can combat the common cold virus by preventing it from hijacking human cells...
Scientists uncover steps to kinase enzyme activation
A new study by the University of Arizona (UA) suggests that revealing all the steps required to activate an enzyme called a protein kinase may help identify new ways to target cancer.
Diabetes researchers find switch for fatty liver disease
Researchers have identified a key in the road for the way the liver deals with carbohydrates, fats and protein...
Charles River Laboratories announces extended relationship with The Michael J. Fox Foundation
Extension includes new project to phenotype Parkinson’s disease models and the continuation of LRRK2 research.
IL1RAP protein boosts multiple oncogenic pathways in AML
Researchers have discovered that a signalling protein elevated in patients with AML plays a much wider role in the disease than previously thought...
13th International Conference on Metabolomics and Systems Biology
Euro Metabolomics 2018 will be a platform to investigate on recent research and advancements that can be useful to the researchers.