Targeting telomerase as therapeutic strategy for melanoma
Combination therapy co-targeting the mitochondria enhances the antitumour effect of telomerase inhibition in NRAS-mutant melanoma.
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Antibodies protect nerve-muscle connections in Lou Gehrig’s disease
A study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of aggressive ALS...
Genetic catalyst identifies the evolution of antibiotic resistance
Researchers have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria...
The role of ‘extra’ DNA in cancer evolution and therapy resistance
A team of scientists have reported that tumour progression was often driven by cancer-promoting genes, known as oncogenes, on extrachromosomal pieces of DNA.
Study unearths how PKC zeta impacts colorectal cancer
Scientists in the United States have investigated the relationship between tumour suppressor, protein kinase C zeta (PKC zeta), and metastatic colorectal cancer.
Cell therapy aids heart recovery
Biomedical engineers invent an innovative technique to help injured hearts regenerate...
Scientists generate an atlas of the human genome using stem cells
Scientists have generated an atlas of the human genome using a state-of-the-art gene editing technology and human embryonic stem cells, illuminating the roles that our genes play in health and disease.
New compound shows promise for stroke recovery
Scientists in the U.S. have reported that an experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can often continue months after a person has suffered the stroke.
GLUT5 fluorescent probe fingerprints cancer cells
Researchers have explained the basic science behind multicolour probes that enable targeting of cancer-relevant fructose transporter, delving into the image-based detection of cancer cells...
Researchers develop a new method to discover drugs to treat epilepsy
Method uncovers a promising new use for a well-known cancer drug in stopping difficult-to-treat seizures...
SMi’s 5th Annual Molecular Diagnostics Conference 2018 agenda released
SMi proudly presents its 5th annual conference on Molecular Diagnostics, taking place at the Holiday Inn Kensington Forum, London, UK on 9 and 10 July 2018, with a half-day post-conference workshops on 11 July 2018...
Stem-cell technology enables creation of neurons to study brain responses of the super obese
Researchers in the U.S. have tested a technology termed ‘disease in a dish’ that uses stem-cell technology to re-create brain neurons of super obese individuals. The goal is to better understand obesity and potentially enable tailored treatments.
Male contraceptive compound stops sperm without affecting hormones
In preclinical tests, researchers have shown how a new compound can immobilise sperm temporarily without side effects...
CRISPR used to edit DNA outside of the cell
Scientists have developed a breakthrough CRISPR gene-editing tool, that could allow researchers to quickly and precisely engineer multiple changes to the genetic code...
Human protein important for cellular communication resembles bacterial toxin
The structure of teneurins, proteins involved in embryonic development and the nervous system, is more like bacterial toxins than any other human protein.