Disrupting macrophage action aids melanoma immunotherapy success
Scientists in Switzerland have uncovered a potential means of increasing effective treatment of melanomas with immunotherapy, by disrupting the action of macrophages.
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New class of drugs could help tackle treatment-resistant cancers
Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...
KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
Sensitive new assay detects hepatitis B infection in single liver cells and serum
Technique measuring the cccDNA marker may allow earlier detection of hepatocellular carcinoma in patients...
Rare brain disease in children: Major breakthroughs in Rasmussen’s encephalitis
Chronic focal encephalitis is a rare and devastating inflammatory brain disease, researchers have proven that the disease attacks patients using their own immune system...
Cryo-electron microscopy reveals structure of a herpesvirus capsid
Researchers have reconstructed the 3.1 Å structure of the herpes simplex virus type 2 (HSV-2) B-capsid and built the atomic model, thus expanding the understanding of the assembly mechanism of the capsid...
FGF21 gene variant found to lower body fat
Researchers have found that a gene that makes humans eat more sugar can also lower body fat...
BNIP1 identified as a risk gene for ALS
Broad data analysis points to genetic similarities between Lou Gehrig's Disease and a form of dementia...
An advance for precision medicine
Discovery allows scientists to index thousands of cells simultaneously, a 40-fold increase from the current method...
A novel pathway to regulate B cell activity and prevent autoimmunity
Researchers at the Medical University of South Carolina (MUSC) have identified a novel checkpoint of peripheral tolerance, specifically in B cells.
Macular degeneration linked to ageing immune cells
Older cells promote inflammation, abnormal blood vessel growth that can lead to blindness...
The National Institutes of Health announce Biobanking Medical Project
SMi Reports: The National Institutes of Health announce one of the most ambitious medical projects in biobanking, which will commence this spring.
Researchers uncover protective role of oestrogen against type-2 diabetes
Scientists in Switzerland reveal the mechanisms behind the protective role of oestrogen against developing type 2 diabetes.
New method allows scientists to watch brain cells interacting in real time
Findings could deepen understanding of neurological disorders...
Study develops compound that activates tumour-fighting iNKT cells
Researchers have discovered a significant new compound that helps to mobilise a type of T cell – invariant natural killer T (iNKT) cells – in the fight against disease.