Human-derived proteins used in DREAM tool
CRISPR-DREAM tool used to activate insufficiently expressed genes and convert skin cells to induced pluripotent stem cells (iPSCs).
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Midbody remnants following mitosis could combat cancer
Midbody’s role in cell signalling and stimulating cell proliferation offers an opportunity to detect cancer.
Pancreatic tumours fooled by glutamine mimic
A novel treatment approach using DON molecule starves tumours of essential nutrient, significantly slowing tumour growth.
AI: age prediction model on human brain tissue developed
For the first time ever, researchers have developed an algorithm to predict age at death and indicate early changes related to disease.
Increased pain sensitivity in Neanderthal gene variants
Three gene variants in SCN9A gene, implicated in sensory neurons and inherited from Neanderthals, result in increased pain sensitivity.
Neutrophils: vital defence against fungal toxin
New research uncovers how neutrophils trigger cellular processes to counteract the Candida albicans toxin.
Gene expression signatures improve prognostic ability
Thousands of breast cancer gene expression signatures analysed.
Spectra: new insights to improve immunotherapy treatments
New open-source computational method called Spectra improves analysis of single-cell transcriptomic data.
Nutrient programmes immune cells to battle infection and cancer
Research suggests immune and non-immune cells can be reprogrammed by changing how nutrients are used.
Vascular cells essential in forming long-term memories
New research reveals capillary cells and neurons work together to ensure memory formation and storage.
Genetic scar left in the genome of bacteria
New study reveals how pneumonia cells become resistant to penicillin through evolutionary gateway.
Childhood cancer survivors’ mortality risk
Researchers find genetic explanation for increased risk of developing second cancers.
Explosive cell death: inflammation-causing gene
WEHI researchers have found that a genetic change of MLKL increases risk of uncontrolled inflammatory response
Proteolysis: new method developed to target cancer cells
Researchers have found that targeting chimeras with click-release proteolysis activates specific molecules that target cancer cells without harming health cells.
Senescent immune cells promote lung tumour growth
A recent study sheds light on an unexpected discovery concerning macrophages, a vital type of white blood cell in the body's defence against infections and tumours.