OTUD7A gene identified as key player in 15q13.3 microdeletion syndrome
Researchers have identified in a mouse model OTUD7A as the gene that accounts for many characteristics of 15q13.3 microdeletion syndrome...
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Study uncovers therapeutic targets for aggressive triple-negative breast cancers
New findings have made inroads into a strategy to identify TNBC tumours at risk for metastasis...
Gene manipulation holds the key to personalised medicine
Researchers propose a novel approach to manipulate genes that may hold the key to the future of personalised medicine...
Chondroitin sulphate nets hold promise for heart failure treatments
Researchers discover molecular nets inside heart muscles which hold promise for new heart failure treatment...
Scientists uncover the secret to how piRNAs defend the genome
Researchers from the University of Chicago have uncovered the mechanism by which small RNA molecules (piRNAs) locate and silence foreign invading genes, whilst avoiding ‘self’ genes.
LiP-mass spectrometric analysis measures molecular interactions
Researchers have systematically analysed and quantified the interactions of all proteins with metabolites on the level of the whole proteome...
New to 2018: The role of artificial intelligence in drug discovery
SMi Reports: SMi’s 2nd annual Drug Discovery conference, taking place in London on 21 and 22 March 2018, will discuss the role of artificial intelligence in drug discovery.
PSMA PET/CT imaging provides precision radiation therapy for prostate cancer
A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy...
Innovation – Ingrained in the DNA of Ion Torrent products
For Thermo Fisher Scientific, 2018 brings with it a suite of new sequencing solutions that continue to promote application flexibility and throughput scalability for oncology, reproductive health, inherited and infectious disease research.
Stealth virus for cancer therapy
Scientists have rebuilt adenoviruses so that they effectively recognise and infect tumour cells.
Interventions increase attendance for diabetic retinopathy screening
Targeted interventions can significantly improve screening for diabetic retinopathy, according to a new Cochrane Systematic Review.
Scientists discover new epigenetic cause of cblC that shifts rare disease paradigm
Researchers in France and Canada have discovered an epigenetic alteration of a vitamin B12 gene – MMACHC – that has significant implications for our understanding of cblC and other rare diseases.
TIMP-1 protein plays role in reducing cancer’s spread
Researchers have found that the TIMP-1 molecule that helps regulate gene expression plays a big role in keeping us safe from the machinations of cancer...
Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
Study suggests PD-1 inhibitors against aggressive pediatric brain cancer subtype
A study has laid the groundwork for the use of PD-1 inhibitors with an aggressive form of brain cancer, namely supratentorial pediatric ependymoma.