Epigenetic compound inhibits the growth of melanoma cells
Researchers have developed a compound that successfully inhibits the growth of melanoma cells by targeting specific epigenetic modifying proteins...
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Thorase protein may be linked to schizophrenia
Epilepsy drug reverses anti-social behaviours in mice with genes that produce variant proteins...
Cellular barcoding helps scientists understand the behaviour of stem cells
Use of labelling technology in mice leads to discoveries in process of natural blood formation...
Bacterial cells designed to reflect sound waves for ultrasound imaging
New technology may one day allow doctors to image therapeutic bacterial cells in patients...
Nano-medicine inhibits progression of pancreatic cancer
Survival rates in pancreatic cancer linked to the inverse correlation between specific oncogene and tumour suppressant microRNA...
Stem cell therapy discovery for age-related macular degeneration
Stem cell-derived retinal cells need primary cilia to support the survival of light-sensing photoreceptors...
Organ-on-a-chip device successfully models heart disease
A new device that models atherosclerosis can help researchers better understand the disease, develop therapies and diagnose blood health...
A2aAR protein holds clues for better drug design
Scientists have investigated a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases...
Researchers create anti-inflammatory antibodies to treat autoimmune disease
Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
FDA approves gene therapy for rare form of vision loss
FDA approves Luxturna for patients with confirmed biallelic RPE65 mutation-associated retinal dystrophy.
CRISPR prevents hearing loss in mice
Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.
Faulty gene could be responsible for some Crohn’s disease cases
Interaction between MDR1 gene and TH17 immune cells in the ileum could hold the key to Crohn's disease in some instances.
MG1 virus destroys HIV-infected cells that standard therapies can’t reach
Researchers from Canada try a new approach to eliminate dormant HIV-infected cells from the body using the MG1 virus.
Assay may boost targeted treatment of non-hodgkin lymphoma
Better subtyping of diffuse large B-cell lymphomas can enhance diagnosis and guide treatment...
Chemical oscillators offer a new level of molecular control
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit computation within molecular systems...