Uncovering the early origins of Huntington’s disease using CRISPR engineered embryonic stem cells
Researchers have developed a system to model Huntington's in human embryonic stem cells...
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ZNF274 deletion reverses Prader-Willi syndrome
Reversing the imprinting that causes Prader-Willi syndrome gives hope that epigenetic diseases can be cured...
DRD2 crystal structure provides antipsychotic drug development tool
Crystal structure of the dopamine 2 receptor bound to an antipsychotic drug provides a much-needed discovery in the quest to create effective drugs with fewer side effects...
Elimination of c-Raf kinase induces regression of advanced lung tumours
A study has shown how the elimination of the c-Raf kinase by genetic manipulation causes the regression of Kras oncogene-driven advanced lung tumours...
Statistical computing tool visualises employment trends in biomedical science
Scientists looking for jobs after completing their training may soon have a new tool that helps them evaluate various career paths...
MSK1 protein keeps metastatic breast cancer cells dormant
A study has identified the genes involved in the latent asymptomatic state of breast cancer metastases...
Systemic clearing of senescent astrocytes presents new therapeutic avenue for Parkinson’s disease
Researchers illuminate a new focal area for Parkinson’s disease therapy after demonstrating the beneficial effects of systemic clearing of senescent astrocytes.
Researchers uncover the origins of leprosy and reason for its drug resistance
Scientists in Switzerland have developed the tools to sequence genes from the leprosy bacterium, Mycobacterium leprae, revealing information about its origins and reasons behind its resistance to drugs.
Blocking 20-HETE chemical counters the siren call of aggressive cancers
Scientists have successfully blocked the powerful call of two types of aggressive cancer – glioblastoma and breast cancer – in laboratory models; with evidence that inhibiting the chemical 20-HETE halts tumour growth.
HIF-1 protein shows promise as a non-hormonal treatment for menorrhagia
Researchers have identified a key protein that could explain why heavy bleeding occurs during menorrhagia, paving the way for potential treatments that avoid the need to take hormones...
Raman imaging technique shows Alzheimer’s disease progress in the brain
Using Raman optical technology, scientists can now produce images of brain tissue that is affected by Alzheimer’s disease...
Cryo-EM reveals critical OST complex and potential drug target
Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, paving the way for the development of new medications...
Altered gut microbiome populations may cause blood infections in paediatric cancer patients
Scientists discover that altered gut microbiome populations appear to influence the onset of blood infections in paediatric cancer patients.
Corning to introduce new dissolvable microcarriers for improved large-scale cell expansion
Corning to unveil new product offerings at Cell & Gene Therapy World in Miami, Fla.
NIH to launch genome editing research program
Somatic Cell Genome Editing aims to develop tools for safe and effective genome editing in humans...
