Cancer-killing T cells enhanced by engineered bacteria
Bacteria programmed to paint targets on solid tumours for T cells to see eliminates the need for specific antigens.
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Huntington’s disease: a way to prevent cognitive decline
Discovery about Huntington’s disease may apply to other neurodegenerative disorders, like Alzheimer’s and frontotemporal dementia.
New material engineered can repair severed nerves
Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.
Protective mutation found in kidney disease gene
A new discovery about a different protective genetic mutation in apolipoprotein L1 could have major implications for kidney health.
SCID-X1 gene therapy successful with 3D genome architecture
New research improves patient care by finding where gene copies integrate into DNA and using lentiviral vectors.
Human-derived proteins used in DREAM tool
CRISPR-DREAM tool used to activate insufficiently expressed genes and convert skin cells to induced pluripotent stem cells (iPSCs).
Midbody remnants following mitosis could combat cancer
Midbody’s role in cell signalling and stimulating cell proliferation offers an opportunity to detect cancer.
Pancreatic tumours fooled by glutamine mimic
A novel treatment approach using DON molecule starves tumours of essential nutrient, significantly slowing tumour growth.
AI: age prediction model on human brain tissue developed
For the first time ever, researchers have developed an algorithm to predict age at death and indicate early changes related to disease.
Increased pain sensitivity in Neanderthal gene variants
Three gene variants in SCN9A gene, implicated in sensory neurons and inherited from Neanderthals, result in increased pain sensitivity.
Neutrophils: vital defence against fungal toxin
New research uncovers how neutrophils trigger cellular processes to counteract the Candida albicans toxin.
Gene expression signatures improve prognostic ability
Thousands of breast cancer gene expression signatures analysed.
Spectra: new insights to improve immunotherapy treatments
New open-source computational method called Spectra improves analysis of single-cell transcriptomic data.
Nutrient programmes immune cells to battle infection and cancer
Research suggests immune and non-immune cells can be reprogrammed by changing how nutrients are used.
Vascular cells essential in forming long-term memories
New research reveals capillary cells and neurons work together to ensure memory formation and storage.