Researchers use AI technology to chart immune cell receptor 10 January 2018 | By Drug Target Review Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical ‘antennas’ on the surface of immune system T-cells.
Modified nanoscale virus could deliver peptide drugs to cells 10 January 2018 | By Drug Target Review By chipping away at a viral protein, Rice University scientists have discovered a path toward virus-like, nanoscale devices that may be able to deliver drugs to cells.
Biomarkers identified that predict immunotherapy success 10 January 2018 | By Drug Target Review Researchers in Switzerland have identified biomarkers in the blood that can predict which patients are likely to respond favourably to immunotherapy treatment for cancer.
Functioning human muscle grown from induced pluripotent stem cells 9 January 2018 | By Dr Zara Kassam (Drug Target Review) First functioning human muscle grown from induced pluripotent stem cells holds promise for cellular therapies, drug discovery and studying rare diseases...
Super-silenced DNA study hints at new ways to reprogram cells 9 January 2018 | By Drug Target Review Newly described stretches of super-silenced DNA reveal a fresh approach to reprogram cell identity.
Scientists develop green fluorescent protein to aid intracellular research 9 January 2018 | By Drug Target Review Researchers at Osaka University in Japan have developed a superior acid-tolerant green fluorescent protein to enhance the study of intracellular molecular dynamics.
Promising preclinical drug candidate suppresses HIV 9 January 2018 | By Dr Zara Kassam (Drug Target Review) A team of researchers have tested a chemical compound that suppresses HIV, protects immune cells, and remains effective for weeks with a single dose...
X chromosome reactivation could treat Rett syndrome 8 January 2018 | By Dr Zara Kassam (Drug Target Review) Reactivation of the inactive X chromosome could lead to an increased expression of the healthy protein underlying the neurodevelopmental disorder...
Near-infrared molecular imaging identifies lung nodules for resection in osteosarcoma 8 January 2018 | By Dr Zara Kassam (Drug Target Review) In a proof-of-principle case report, researchers announce that targeted fluorescence successfully identified pulmonary metastases in a patient with osteosarcoma...
Precision editing of gut bacteria used to treat colitis 8 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have used precision editing of the bacterial populations in the gut to prevent or reduce the severity of inflammation in a mouse model of colitis...
Anti-obesity drug shrinks fat without suppressing appetite 5 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have discovered a drug that has been shown to selectively shrink excess fat by increasing fat cell metabolism...
Brainstem changes identified in Parkinson’s disease 5 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death...
CXCR4 receptor provides therapeutic target for ovarian cancer 5 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have described a key cellular receptor in the processes of metastasis in ovarian cancer, the findings may lead to the use of CXCR4 inhibitors as a therapeutic target...
Epigenetic compound inhibits the growth of melanoma cells 4 January 2018 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a compound that successfully inhibits the growth of melanoma cells by targeting specific epigenetic modifying proteins...
Thorase protein may be linked to schizophrenia 4 January 2018 | By Dr Zara Kassam (Drug Target Review) Epilepsy drug reverses anti-social behaviours in mice with genes that produce variant proteins...
