Phenogenetic map created for stem cell models of neurological diseases
Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...
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Peripheral T-cell lymphoma linked to textured breast implants
Researchers have analysed a rare peripheral T-cell lymphoma that may develop as a result of breast implants...
dCA accelerates HIV-1 suppression in chronically infected cells
Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...
Synthetic compound targets energy generation of metastatic cancer cells
Researchers have developed a synthetic compound that targets the enzyme FerT, thereby killing metastatic cells...
Cryo-MOST approach maps whole-brain changes in Alzheimer’s disease
Micron-level, 3-D visualisation of protein deposits found in Alzheimer's disease could speed development of new treatments...
CRISPR used to identify drug target for bowel cancer
CRISPR used to identify a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies...
Gene transcription in CD8 T cells differentiates chronic from resolving HCV
Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
Macrophages play critical role in sustained delivery of MD therapy
Inflammatory cells retain drug after it disappears from circulation, improving delivery to regenerating muscle cells...
MS risk in children detected with MRI brain scans
MRIs can reveal changes in the brain associated with MS before the clinical symptoms of the disease appear in children...
Antibiotic resistance genes identified
By analysing large volumes of DNA data, researchers have identified 76 new types of antibiotic-resistant genes...
Modified CRISPR technique used to combat Parkinson’s disease
Biological engineers identify genes that protect against protein linked to Parkinson's disease...
A3G protein fights HIV as monomer and dimer
A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...
N-alpha-acetyltransferase D found to promote lung cancer progression
NatD, which mediates N-alpha-terminal acetylation of histone H4, found to promote lung cancer progression...
Research reveals antibody treatment pathway for severe allergic asthma
Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...
Cell contacts in embryonic development determine cellular fate
Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...