Self-regulating nanoparticles could treat cancer
Scientists have developed 'intelligent' nanoparticles which heat up to a temperature high enough to kill cancerous cells...
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Five new malaria targets that could lead to an effective vaccine
Scientists have identified five targets that reduce the parasite's ability to invade red blood cells...
yTRAP used to quantitatively measure and manipulate protein aggregation
Researchers have built a synthetic genetic tool yTRAP to quantitatively sense, measure and manipulate protein aggregation in live cells...
Inhibiting β-lactamase may reverse antibiotic resistance
By developing a chemical to inhibit β-lactamase enzymes, a significant proportion of antibiotic resistance may successfully be reversed...
Alpha-1 antitrypsin deficiency shows promise in rare liver disease
Nuclease-free gene editing has been found to correct mutated cells ...
Key psychiatric drug target comes into focus
Researchers have reported a major step forward towards designing more powerful psychiatric drugs with fewer side effects...
Discovery lights path for Alzheimer’s research
Researchers identify binding site on the amyloid beta peptide that could facilitate better drugs to treat the disease...
Phenogenetic map created for stem cell models of neurological diseases
Researchers have performed meta-analysis of neurological and neurodegenerative diseases and created an atlas of how cell characteristics are linked to their genotype...
Peripheral T-cell lymphoma linked to textured breast implants
Researchers have analysed a rare peripheral T-cell lymphoma that may develop as a result of breast implants...
dCA accelerates HIV-1 suppression in chronically infected cells
Didehydro-Cortistatin A effectively suppresses production of the HIV virus in chronically infected cells and prevents viral rebound...
Synthetic compound targets energy generation of metastatic cancer cells
Researchers have developed a synthetic compound that targets the enzyme FerT, thereby killing metastatic cells...
Cryo-MOST approach maps whole-brain changes in Alzheimer’s disease
Micron-level, 3-D visualisation of protein deposits found in Alzheimer's disease could speed development of new treatments...
CRISPR used to identify drug target for bowel cancer
CRISPR used to identify a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies...
Gene transcription in CD8 T cells differentiates chronic from resolving HCV
Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
Macrophages play critical role in sustained delivery of MD therapy
Inflammatory cells retain drug after it disappears from circulation, improving delivery to regenerating muscle cells...