Synthetic compound targets energy generation of metastatic cancer cells 18 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have developed a synthetic compound that targets the enzyme FerT, thereby killing metastatic cells...
Cryo-MOST approach maps whole-brain changes in Alzheimer’s disease 18 October 2017 | By Nic Losardo (Drug Target Review) Micron-level, 3-D visualisation of protein deposits found in Alzheimer's disease could speed development of new treatments...
CRISPR used to identify drug target for bowel cancer 17 October 2017 | By Dr Zara Kassam (Drug Target Review) CRISPR used to identify a new drug target for bowel cancer that is specific to tumour cells and therefore less toxic than conventional therapies...
Gene transcription in CD8 T cells differentiates chronic from resolving HCV 17 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified differences in gene transcription within key immune cells that may distinguish those individuals infected with HCV...
Macrophages play critical role in sustained delivery of MD therapy 16 October 2017 | By Dr Zara Kassam (Drug Target Review) Inflammatory cells retain drug after it disappears from circulation, improving delivery to regenerating muscle cells...
MS risk in children detected with MRI brain scans 16 October 2017 | By Nic Losardo (Drug Target Review) MRIs can reveal changes in the brain associated with MS before the clinical symptoms of the disease appear in children...
Antibiotic resistance genes identified 16 October 2017 | By Dr Zara Kassam (Drug Target Review) By analysing large volumes of DNA data, researchers have identified 76 new types of antibiotic-resistant genes...
Modified CRISPR technique used to combat Parkinson’s disease 13 October 2017 | By Dr Zara Kassam (Drug Target Review) Biological engineers identify genes that protect against protein linked to Parkinson's disease...
A3G protein fights HIV as monomer and dimer 13 October 2017 | By Dr Zara Kassam (Drug Target Review) A human protein A3G inhibits HIV-1 by acting as a roadblock for further replication of the virus...
N-alpha-acetyltransferase D found to promote lung cancer progression 13 October 2017 | By Dr Zara Kassam (Drug Target Review) NatD, which mediates N-alpha-terminal acetylation of histone H4, found to promote lung cancer progression...
Research reveals antibody treatment pathway for severe allergic asthma 13 October 2017 | By Dr Zara Kassam (Drug Target Review) Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...
Cell contacts in embryonic development determine cellular fate 12 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have identified a positive feedback loop between the duration of cell-cell contacts and the specification of a cell's fate...
Mitochondrial DNA could predict risk for sudden cardiac death 12 October 2017 | By Dr Zara Kassam (Drug Target Review) New studies add to evidence of link between mitochondrial DNA copy number and risk for cardiovascular disease...
Stem cell line offers expanded potential for research and treatments 11 October 2017 | By Dr Zara Kassam (Drug Target Review) Researchers have created Expanded Potential Stem Cells that have greater potential for embryonic development than current stem cell lines...
Richard Goodwin joins DTR Advisory Board 11 October 2017 | By Steve Bremer (Drug Target Review) Dr Goodwin is the latest top-level scientist to join DTR's advisory board
