Underlying genetic causes of congenital heart disease identified
Researchers have helped shed light on some of the underlying genetic causes of CHD as well as the long-term outlook for patients who carry these mutations...
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Link between bacterial imbalances and breast cancer identified
Bacterial composition of breast tissue could offer a new perspective in the battle against breast cancer...
Microcapsules to enhance the efficiency of genome-editing
Researchers have found that polymer and hybrid silica-coated microcapsules are efficient in genome-editing...
Potential targets for treatment of leishmaniasis identified
Brazilian scientists show that parasite's penetration of host cells increases expression of certain microRNAs capable of inhibiting the action of the immune system...
PET tracer identifies bacterial infections
The new imaging agent offers a non-invasive method of detecting infection and monitoring antibiotic therapy...
CRISPR-engineered cancer model to test therapeutics
A new technique for modelling leukaemia may aid drug discovery...
Imaging agents developed to better monitor growth of tumours
Imaging agents developed to better monitor the growth of tumours and generate new therapies...
DNA-based Zika vaccine found effective at inducing immune response
A new generation DNA-based Zika vaccine is the first to demonstrate both safety and the ability to elicit an immune response against Zika in humans...
E6/Myc binding provides potential treatment strategy for HPV
A study that teases apart the biological mechanisms by which HPV cause cancer, has found a strategy that may provide targeted treatment...
NRF2 pathway provides new approach to cancer drug discovery
Scientists have developed a promising new strategy for the discovery of novel anti-cancer therapies for non-small-cell lung cancers...
Metabolic collaboration linked to Alzheimer’s disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
Scientists develop broad-spectrum inhibitors of influenza virus
Scientists have developed broad-spectrum inhibitors of the influenza virus using artificial peptide molecules...
Novartis and UC Berkeley collaborate to tackle ‘undruggable’ disease targets
Collaboration aims to unlock difficult drug targets and accelerate the discovery of new medicines in areas such as infectious diseases and cancer...
CRISPR-Cas9 used to systematically inactivate genes in colorectal cancer
Researchers have used CRISPR-Cas9 to inactivate genes in human colorectal cancer cell lines -- one with normal KRAS gene and one with a mutant KRAS...
Parkinson’s UK Drug Discovery Manager joins DTR advisory board
Drug Target Review welcomes Janusz Kulagowski to its advisory board ...