Bacterial antibiotic resistance pathways identified
Researchers have described two structures and mechanisms - efflux pumps and reinforced cell walls - that certain disease-causing bacteria use to keep antibiotics away...
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New marker could refine the process of producing hPSC-derived insulin cells
Scientists at the University of Copenhagen have identified a unique cell surface protein present on human pancreatic precursor cells providing for the first time a molecular handle to purify the cells whose fate is to become cells of the pancreas - including insulin producing cells.
New biomarkers found for cystic fibrosis
Canadian researchers have identified several unknown chemicals that were consistently associated with babies who had cystic fibrosis (CF), including two different drug and environmental compounds the infants secreted in sweat at much lower concentration levels...
Hamish Ryder joins Drug Target Review Advisory Board
Prior to joining CRT-DL, Dr Ryder held positions in pharmaceutical and biotech companies for over 20 years ...
Genetic testing may detect childhood epilepsy
Specific genetic factors have been found to be the cause of epilepsy in 40 percent of patients evaluated with seizures...
Metrion extends collaboration with LifeArc
Metrion Biosciences Limited and LifeArc, today announced an extension of their existing partnership...
Imfinzi wins breakthrough therapy designation
AstraZeneca and MedImmune, have today announced that the US Food and Drug Administration has granted breakthrough therapy designation for Imfinzi for the treatment of patients with locally-advanced, unresectable non-small cell lung cancer...
Cancer Research UK brings commercialisation arm in-house
The move will help funded research progress toward the development of new therapeutics
Immune system may mount an attack in Parkinson’s disease
T cells may play an important role in Parkinson’s disease (PD), according to a new study...
Imaging technique overturns longstanding DNA folding model
Researchers have developed an electron microscopy technique that enables the 3D structure and packing of DNA to be visualised inside the cell nucleus of intact cells.
Novel perspectives on anti-amyloid treatment for the prevention of Alzheimer’s
A collaboration between Prof Lucía Chávez-Gutiérrez and Prof Bart De Strooper of VIB-KU Leuven has revealed the molecular basis of the hereditary form of Alzheimer’s disease that strikes early in life.
Biomarkers show promise as Alzheimer’s diagnostic tool
Physical biomarkers have been discovered that may help diagnose the changes to proteins found in the spinal fluid and blood of Alzheimer's patients...
VRC01 antibody may prolong time to HIV viral rebound
A study has shown the infusion of a broadly neutralising antibody (VRC01) in virally suppressed volunteers associated with a modestly delayed rebound of HIV...
Researchers use CRISPR-Cas9 to target retinal angiogenesis.
Researchers have used CRISPR-Cas9 to target retinal angiogenesis via an adeno-associated virus to deliver genomic edits to target vascular endothelial cell growth factor...
US Phase 2 trial to test targeted drugs in paediatric tumours
Phase 2 trial to explore targeted therapies for children with solid tumours that harbour specific genetic mutations which have progressed during or after standard therapy...