Proteomics accurately detect exposure to Zika virus
Researchers have used proteomics to examine proteins and peptides in saliva to accurately detect exposure to Zika virus...
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Immune system can be modulated by targeted manipulation
Manipulation of the sugar metabolism and associated modulation of the immune system could open up new options for treating specific infectious and also autoimmune diseases...
GIST tumours linked to NF1 mutations
Researchers have determined that a specific region of the duodenal-jejunal flexure, shows a high frequency of gastrointestinal stromal tumours with mutations of the NF1 gene...
Novel imaging approach offers insights into HIV’s lifecycle
Scientists have used a novel live-cell fluorescent imaging system that has allowed them to identify individual particles associated with HIV...
Histone 1, the guardian of genome stability
Researchers have explained for the first time that the suppression of histone 1 causes cell damage and genomic instability...
Two-step process leads to cell immortalisation and cancer
New research, has studied the immortalisation process using genome-engineered cells...
Novel immunotherapy technology for prostate cancer
Scientists have described a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA...
Researchers find switch that turns on immune cells tumour-killing ability
Researcher have shown how a mRNA molecule known as Lethal-7 serves as a molecular control hub to direct the function of cytotoxic T lymphocytes...
Researchers identify powerful pain reliever
A team of scientists have discovered what they say is a powerful pain reliever that acts on a previously unknown pain pathway...
Fostering a culture of innovation to drive growth
At Charles River, we are passionate about fostering innovation as our commitment to ensure clients are provided with the most efficient path to market...
New imaging technique may predict the of spread breast cancer
Researchers have developed a radioactive ‘tracer’ molecule to detect myeloid-derived suppressor cells’ accumulating in the lung in preparation for the arrival of breast cancer cells...
Potential broad-spectrum antiviral discovery for herpes virus
Scientists studying cellular enzyme complexes have unexpectedly found that inhibiting EZH2/1 suppressed viral infection in the herpes simplex virus infection...
New synthetic polio vaccine candidate
A collaborative team of scientists have developed a novel synthetic vaccine with a method grown in plants that uses virus-like particles...
New genetic analysis reveals early diagnosis for breast cancer
Researchers have shown that catching and treating breast cancer before it spreads is now a realistic goal...
Tumours detected with sugar molecules
Scientists have synthesised a complex sugar structure that specifically binds to the tumour protein Galectin-1...