New cancer drug tested in mice may benefit certain leukaemia patients
Almost 6,000 new cases of acute lymphoblastic leukaemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.
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Balance and movement improved in animal model of Parkinson’s disease
Researchers have developed a molecular compound that improves balance and coordination in mice with early stage Parkinson's disease.
Artificial intelligence to assist in the treatment of heart patients
Artificial intelligence can be used to recognise difficult to predict complications as early as possible within the home care of heart patients.
Arming T-cells to channel aggression against cancer
Scientists have armed immune cells with a new surface molecule that causes them to respond aggressively when they encounter a protein that tumours actually use to camouflage themselves from the immune system. Researchers from the Helmholtz Zentrum München and various partners introduced the method in ‘Cancer Research’.
New leukaemia treatment outperforms standard chemotherapies
Researchers at The Australian National University (ANU) are working on a new treatment for an aggressive type of leukaemia that outperforms standard chemotherapies.
Snake venom might provide a safer antiplatelet drug
In preliminary research, an antiplatelet drug based on a snake venom protein prevented blood clotting without leading to excessive bleeding, a dangerous side effect of currently available antiplatelet drugs. The venom protein may be the template for a new class of antiplatelet drugs that offers fewer bleeding complications.
Newly discovered disease mechanism for type 2 diabetes
A newly discovered mechanism behind reduced insulin production in type 2 diabetes is now being presented.
SOPHiA artificial intelligence empowers liquid biopsies to fight cancer
Sophia Genetics injects artificial intelligence in liquid biopsies to accelerate early detection of cancer and monitor treatments’ effectiveness.
‘Immunoswitch’ particles may be key to more effective cancer immunotherapy
Scientists have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells’ defensive properties while switching on a robust anti-cancer immune response in mice.
Researchers identify a key controller of biological machinery in cell’s ‘antenna’
St. Jude Children’s Research Hospital discovery of a regulatory enzyme working at the primary cilium could lead to treatments for the brain tumour medulloblastoma.
A method to improve in vitro tests
Before new nanoparticles or other nanomedicines can be injected into the human body, a whole series of tests must be conducted in the laboratory, then in living cells, and in the end on humans.
Micro-gene protects the brain from developing epilepsy
A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice.
Dogs help in breast carcinoma research
Cancer of the mammary glands in dogs is very similar to human breast carcinoma. For this reason, treatment methods from human medicine are often used for dogs.
Eisai and Charles River Laboratories announce extension of integrated drug discovery partnership
Companies to continue collaboration in discovery of next generation anti-malaria drugs...
Diabetes drug prevents cardiovascular disease in obese mouse study
A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.