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Diabetes drug prevents cardiovascular disease in obese mouse study

6 June 2017 | By University of Missouri-Columbia

A study by researchers at the University of Missouri School of Medicine found that the diabetes medication linagliptin can protect against stiffening of the left ventricle of the heart in overweight female mice. The finding may have implications for management of cardiovascular disease in humans.

Cells change type to help or hinder immunity

6 June 2017 | By Sarah Wills (Drug Target Review)

Scientists have discovered a mechanism that provides a possible new target for allergy treatments, which may bring hope for asthma sufferers.

Attacking metastatic tumours in the brain

6 June 2017 | By Niamh Marriott (Drug Target Review)

Targeting HER3 could cripple metastatic cancers that have spread to the brain...

The gut microbiota plays key role in diabetes treatment

2 June 2017 | By Niamh Marriott (Drug Target Review)

A clearer picture of how the classic diabetes medication metformin works has emerged.

Scientists give tumour-fighting cells a boost in battling bone marrow cancer

2 June 2017 | By Niamh Marriott (Drug Target Review)

Researchers uncovered a new way to enhance the function of a specific type of immune cell that destroys tumours in multiple myeloma...

Human Cell Atlas data platform kicks off with support from CZI

2 June 2017 | By Niamh Marriott (Drug Target Review)

The Chan Zuckerberg Initiative announced financial support for the Human Cell Atlas, which uses sequencing technology to redefine every cell in the body...

SOPHiA AI unlocks power of exome sequencing for clinical diagnostics

1 June 2017 | By Niamh Marriott (Drug Target Review)

SOPHiA AI demystifies the secrets of the exome, home to 85% of disease-causing genetic variants. Clinicians can now get highly accurate results to diagnose patients for rare hereditary disorders.

Queen’s researchers breakthrough discovery in fight against bowel cancer

1 June 2017 | By Niamh Marriott (Drug Target Review)

New research led by Queen’s University Belfast has discovered how a genomic approach to understanding bowel cancer could improve the prognosis and quality of life for patients.

The immune system promotes spontaneous heart regeneration

1 June 2017 | By Niamh Marriott (Drug Target Review)

In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.

New mouse model to better kidney cancer treatment

31 May 2017 | By Niamh Marriott (Drug Target Review)

Research in the field of kidney cancer, also called renal cancer, is vital, because many patients with this disease still cannot be cured today.

Healing wounds with cell therapy

31 May 2017 | By Niamh Marriott (Drug Target Review)

An experimental treatment in mice allows the reprogramming of blood cells in order to promote the healing process of cutaneous wounds...

New antibiotic packs a punch against bacterial resistance

31 May 2017 | By Niamh Marriott (Drug Target Review)

Scientists have given new superpowers to an antibiotic called vancomycin, an advance that could eliminate the threat of antibiotic-resistant infections.

Optibrium, Imperial College and DNDi to collaborate on drug development

30 May 2017 | By Niamh Marriott (Drug Target Review)

The collaboration will provide MSc students with industry-relevant learning tools and pharma with a new pipeline of candidate compounds.

Scientists jump hurdle in HIV vaccine design

30 May 2017 | By Niamh Marriott (Drug Target Review)

Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design.

CRISPR gene editing can cause hundreds of unintended mutations

30 May 2017 | By Niamh Marriott (Drug Target Review)

As CRISPR-Cas9 starts to move into clinical trials, a new study has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.

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