Proteolysis: new method developed to target cancer cells
Researchers have found that targeting chimeras with click-release proteolysis activates specific molecules that target cancer cells without harming health cells.
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Senescent immune cells promote lung tumour growth
A recent study sheds light on an unexpected discovery concerning macrophages, a vital type of white blood cell in the body's defence against infections and tumours.
Novel approach to overcome resistance to cancer drugs
Researchers at the University of Queensland have discovered a promising drug target capable of addressing drug resistance and preventing tumour regrowth in cancer patients.
Advancing obesity and diabetes therapy with brown fat cells
Researchers discover the intricate cellular signalling cues that orchestrate the formation of brown adipocytes in mice.
Engineered immune cells for improved cancer defence
A collaborative team has uncovered a method to extend the functionality of CAR-T cells.
PCOS: stem cell-derived components
Polycystic ovary syndrome (PCOS) is a widespread endocrine disorder affecting millions of women worldwide, profoundly impacting their hormonal equilibrium, fertility, and overall quality of life. This enigmatic condition, characterised by diverse symptoms and complex underlying causes, has long eluded effective treatment.
Cancer inhibitors shows success in slowing tumour growth
Researchers have successfully demonstrated the potential of using a combination of inhibitors to effectively curb tumour growth and stave off relapses in patients afflicted with specific cancers.
Telomeres linked to higher dementia risk
A study proposes that shorter telomeres at the tips of chromosomes in white blood cells might indicate an elevated risk of dementia.
COVID-19: rapid and reliable detection method
Commercially available mass spectrometers offer a reliable means of detecting the SARS-CoV-2 coronavirus.
Japanese squirrels develop human hereditary diseases with ageing
Researchers at Tokyo University of Agriculture and Technology, led by Dr Tomoaki Murakami, have uncovered a previously undocumented disease, fibrinogen Aα-chain amyloidosis, highly prevalent in Japanese squirrels, shedding light on its parallels with the human condition. Their findings offer new insights into amyloidosis and its potential implications for medical research.
New test promises better detection of elusive cervical cancers
Researchers have developed a novel test capable of detecting a form of cervical cancer that frequently eludes detection through traditional Pap tests.
New cell discovery shakes up neuroscience
Scientists have identified a novel cell type that combines astrocytic characteristics with the machinery for synaptic transmission. This discovery resolves years of debate in the field.
Newly identified cell type uncovered in the thymus
Microfold cells (M cells) are primarily known for their role in the intestinal epithelium. However, the researchers discovered similar cells in the thymus.
Multiomics approach unveils flu severity insights
Some individuals may experience more severe symptoms when infected with the same virus compared to others. The reasons behind this variability are not yet fully understood. While viral factors, such as differences in the virus strain, do play a role, they cannot account for the diverse responses observed among individuals…
Combating malaria: new approach
Researchers are actively seeking to unravel the intricacies of gene expression regulation throughout the various stages of the P. falciparum lifecycle.