Vaccines against parasitic disease
In Columbus, Ohio, scientists have made significant strides in developing vaccines to combat leishmaniasis, a disfiguring skin disease, through animal studies.
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Dectin-1: HIV and ageing
New study aimed to assess how Dectin-1 functions in myeloid cells among various cohorts of individuals.
Novel based editors developed
Researchers have developed a novel based CRISPR-free base editing system named CyDENT, which enables precise base editing.
Research offers insight into swift spread of SARS-CoV-2 variants
Researchers have shown insights into the omicron variants of the SARS-CoV-2 virus, which have rapidly disseminated globally in the past year.
Immune cells predict flu symptoms
St. Jude Children’s Research Hospital, in collaboration with ESR Limited, discovered that specific immune cells present in individuals months before a flu infection can better predict symptom development compared to current antibody-based methods.
Vaccine may reduce severity of long-haul covid symptoms
Receiving a COVID-19 vaccination could offer a dual benefit by not only lowering the likelihood of developing long-haul COVID but also mitigating symptoms for individuals already dealing with this condition.
Immunotherapy: antibody set for combating tumours
A recent study sheds light on the potential of artificial DNA structures that, when combined with antibodies, guide the immune system to target cancer cells specifically.
Protein-triggered motor neuron loss in amyotrophic lateral sclerosis
The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the cerebral cortex to motor neurons in the spinal cord, which in turn activate muscles, enabling fluid motion.…
DNA repair breakthroughs for innovative cancer treatment
This study explores cell survival, the continuous repair of DNA breaks is crucial. Failure to repair DNA effectively can result in mutations, contributing to the development of cancer.
Modified neural stem cells for spinal cord injury
Using genetically modified human neural stem cells (hNSCs), researchers demonstrated that targeted manipulation of a specific gene expression within hNSCs can facilitate the restoration of damaged neural circuits and recovery of locomotor functions.
Dynamic molecular aggregates within cells
Researchers from the University of Freiburg and the University of Cambridge have observed live cell formation of membraneless molecular aggregates, uncovering the interplay between biological mechanisms and physical force.
CDK9 inhibitors for haematological malignancy treatment
A novel category of drugs, CDK9 inhibitors, emerges as potent agents capable of suppressing the transcription of these anti-apoptotic and pro-survival proteins.
Artificial intelligence cell analysis for swift blood disease diagnosis
Researchers from the German Cancer Research Center (DKFZ) and the Cambridge Stem Cell Institute have developed an artificial intelligence (AI) system capable of identifying and characterising white and red blood cells within microscopic images of blood samples. This AI algorithm holds the potential to aid medical professionals in diagnosing blood…
Neuronal relocation facilitates healthy retina formation
During embryogenesis, organs must achieve a precise cell count and functional structure. Embryos efficiently manage multiple tasks—growth, shaping, and architecture establishment. Despite extensive research on embryonic development, the intricate coordination of these tasks in both space and time remains incompletely understood.
Sickle cell anaemia: gene therapy insights for blood disorders
Cutting-edge research conducted by experts at Michigan Medicine, the Children’s Hospital of Philadelphia, and Penn Medicine is revolutionising the approach to treating blood disorders like sickle cell anaemia through innovative gene therapy methods.