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Promising preclinical findings for Probiodrug’s glutaminyl cyclase inhibitor

8 September 2016 | By Caroline Richards, Editor, European Pharmaceutical Review & Drug Target Review

In a mouse model of inflammation (thioglycollate-induced peritonitis), PQ912 had an effect on recruitment of macrophages and eosinophils, and levels of chemokines and lipid mediators, which the company believes makes QC inhibition attractive for further evaluation as potential anti-inflammatory drug and/or resolution promoting agent...

BioMed X to collaborate with Johnson & Johnson on oral biofilm research

6 September 2016 | By Niamh Louise Marriott, Digital Content Producer

This research group is seeking the potential to unravel novel methods to remove bacterial biofilms from oral surfaces. Oral biofilms consist of a large variety of microorganisms embedded in a complex and robust extracellular matrix...