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Sea sponge reduces pancreatic tumour size

18 August 2016 | By Niamh Louise Marriott, Digital Content Producer

A deep-water marine sponge collected at Fort Lauderdale's coast contains leiodermatolide, a natural product that inhibits the growth of cancer cells as...

Leukaemia blood testing unearths vesicle discovery

17 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Cancerous acute lymphoblastic leukaemia cells produce and release special structures that can be traced in the blood, and therefore could have major implications on the diagnosis, monitoring, drug delivery and treatment of childhood leukaemia...

CRISPR gene editing could treat sickle cell disease

15 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Foetal haemoglobin lacks beta sub-units and has gamma sub-units instead. Thus, beta-thalassemia or SCD–associated mutations, which impair the production or function of the beta sub-unit, do not cause problems with foetal haemoglobin, which can transport oxygen effectively in adults...

New protein target could treat genetic cause of ALS

15 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Targeting a single protein, SUPT4H1, reduces the levels of the three toxic entities created by the C9orf72 gene expansion, the most common genetic cause of ALS...

Alzheimer’s research shows period pain-killer completely reverses memory loss

11 August 2016 | By University of Manchester

Transgenic mice that develop symptoms of Alzheimer's disease were used with one group of 10 treated with mefenamic acid, and 10 with a placebo. The mice were treated at a time when they had developed memory problems. After one month's treatment, memory loss was completely reversed back to the levels…

Killing three deadly diseases with one compound

9 August 2016 | By Niamh Louise Marriott, Digital Content Producer

Three diseases; Chagas disease, leishmaniasis and sleeping sickness, all caused by parasites called ‘kinetoplastids, all sharing similar biology and genetics, leading scientists to investigate the possibility of a single chemical to destroy all three...

Snake gene could hold answer to spinal cord regeneration

8 August 2016 | By Instituto Gulbenkian de Ciência

Researchers from the Instituto Gulbenkian de Ciência, Portugal, have discovered that the key controller of trunk, tail and spinal development is the Oct4 gene, one of the essential regulators of stem cells. The team intend to use their data to open new avenues to the study of spinal cord regeneration...

Flu vaccines fail to protect obese mice

8 August 2016 | By St. Jude Children’s Research Hospital

Using vaccines prepared from killed viruses, the scientists targeted an influenza A H1N1 seasonal flu strain, finding that obese mice are not protected against influenza infections through vaccines, raising concerns about vaccine response in obese humans, who are known to be at an increased risk for severe flu...