Epiregulin identified as a possible target in lung cancer
8 April 2016 | By Victoria White, Digital Content Producer
A study found that in addition to decreased overall tumour burden, mice lacking epiregulin also showed reduced inflammation...
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Cancers can resist treatment by ‘stealing’ blood vessels
8 April 2016 | By Victoria White, Digital Content Producer
A new study is the first to show that tumours can become resistant to drugs over time by learning to steal normal blood vessels from surrounding tissue...
Nanoparticles show promise for treating inflammatory bowel disease
8 April 2016 | By Victoria White
Nanoparticles designed to block a cell-surface molecule that plays a key role in inflammation could be a safe treatment for inflammatory bowel disease...
MRC Technology appoints two new members to its board of trustees
7 April 2016 | By Victoria White, Digital Content Producer
MRC Technology has appointed Dr Les Hughes and Dr Mike Romanos to the board of trustees, effective 1 March 2016...
Allergan signs $3.35 billion Alzheimer’s treatment deal with Heptares
7 April 2016 | By Victoria White, Digital Content Producer
Allergan is to license exclusive global rights to a broad portfolio of novel subtype-selective muscarinic receptor agonists in development by Heptares...
MRC Technology and IPS-CAS in antibody drug discovery collaboration
6 April 2016 | By Victoria White
The parties created IPS-MRCT Joint Centre for Therapeutic Antibodies in order to combine their expertise in research and development...
Allergan and Pfizer terminate merger agreement
6 April 2016 | By Victoria White
The decision was driven by the actions announced by the US Department of Treasury to reform inversion tax rules, which the companies concluded qualified as an “Adverse Tax Law Change”. Market rumour suggests that Pfizer will now target Shire or AstraZeneca and shares in both companies went up with the…
First glimpse of an immature HIV-neutralising antibody
6 April 2016 | By Victoria White
Scientists have described the first-ever immature antibody found in a powerful class of immune molecules effective against HIV. TSRI biologist Jiang Zhu called the antibody a “teenager” and said it gives scientists a unique view of the steps needed to prompt the immune system to effectively target HIV...
TSRI scientists get grant to develop treatments for addiction and mood disorders
6 April 2016 | By Victoria White
Laura Bohn, principal investigator of the project, will focus on the kappa opioid receptor, which helps regulate the release of dopamine...
New mouse model for Zika to aid vaccine research
5 April 2016 | By Victoria White
The mouse model of Zika mimics aspects of the infection in humans, with high levels of the virus seen in the mouse brain and spinal cord...
New method inhibits the growth of TB causing bacteria
5 April 2016 | By Victoria White
A research team investigated the impact of compounds related to cholesterol on the TB causing bacterium Mycobacterium tuberculosis...
NIAID awards $3.1m in grants for research into vaccine adjuvants
5 April 2016 | By Victoria White
Research will include studies into how combinations of adjuvants interact with the immune system, and how synergies between adjuvants can be optimised...
Astellas and AIST enter Chagas’ disease collaboration
1 April 2016 | By Victoria White
Astellas and AIST aim to discover new drugs using genome editing technology and a high throughput activity assay for Trypanosoma cruzi...
Prosthetic ovary implant restores fertility in mice
1 April 2016 | By Victoria White
Researchers hope to use the technology to develop an ovary bioprosthesis that could be implanted in women to restore fertility...
Zika virus structure revealed by Purdue scientists
1 April 2016 | By Victoria White
Researchers have determined the structure of the Zika virus, revealing insights critical to the development of effective antiviral treatments and vaccines...