New algorithm can predict diabetic kidney disease
Researchers from US and Hong Kong have found that a simple blood sample may help doctors catch kidney disease earlier in type 2 diabetes patients
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Placenta’s role in genetic risk of schizophrenia
A recent study led by the Lieber Institute for Brain Development has revealed that over 100 genes associated with the risk of schizophrenia appear to contribute to the development of the illness primarily through their influence on the placenta.
New gene linked to Malaria parasite’s chloroquine resistance
Researchers have important implications for the ongoing fight against malaria, a disease that affects approximately 247 million individuals and causes over 619,000 deaths each year, predominantly among young children.
Gut bacterial interactions limit antibiotic efficacy on C. difficile
A recent study from the University of Wisconsin-Madison suggests that interactions between gut bacteria can influence the effectiveness of antibiotics against C. difficile infections.
Novel approach stimulates DNA repair mechanisms to combat a leading cause of autism spectrum disorders
US researchers report promising results for fragile X syndrome, by stimulating cells' DNA repair mechanisms that could correct the inherited genetic defect associated with the disorder.
Molecular biology behind memory development in early childhood
Researchers from Canada develop a greater understanding about the molecular mechanisms for memory development in early childhood.
New study uncovers DNA repair mechanism in bacterial cells
US research reveals mechanism used by bacterial cells to repair their faulty DNA, which could help scientists understand the intricacies of DNA repair processes.
Diagnosing inflammatory diseases with synthetic peptides
Researchers from Switzerland identify peptides that detect and measure a key biomarker in inflammatory conditions.
Examining brain’s glymphatic system may shed light on brain diseases
US researchers used focused ultrasound with microbubbles to examine glymphatic system of the brain, which plays a crucial role in clearing metabolic waste from the brain.
Linking air pollution and lung disease
USC researchers gain valuable insights into the biological processes underlying the association between air pollution and lung disease. By unravelling the mechanisms involved, researchers are hopeful that new strategies can be developed to mitigate the adverse effects of pollution exposure and improve the prevention and treatment of related diseases.
Targeted therapy for treatment-resistant breast cancer
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.
3D models used to investigate bacteria motility
US researchers created a 3D model of the bacteria: Helicobacter pylori, to better understand its motility, in order to develop new treatments for bacterial infections.
Potential pathway to improved stroke recovery
Japanese researchers identify a protein that reduces inflammation, stimulates neural growth, and improves sensory and motor functions following ischemic stroke in mice.
Diverse senescent cell populations uncovered by single-cell RNA sequencing
Single-cell transcriptomic RNA sequencing analysis has allowed US researchers to identify the specific populations and the dynamic transition states during senescence initiation and progression.
USC researchers zoom into human genome with mammal DNA
USC researcher Dr Steven Gazal and his team have identified human genome base pairs that have remained constant over millions of years of mammalian evolution. These base pairs are linked to human disease. Using DNA from 240 mammal species, they identified genetic variations affecting an individual's survival and reproduction.