Cellectis files clinical trial application for UCART19 in leukaemia
4 January 2016 | By Victoria White
UCART19 is a potential best-in-class allogeneic Talen gene edited T-cell product for treatment of CD19 expressing haematological malignancies...
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Baxalta and Symphogen enter immuno-oncology collaboration
4 January 2016 | By Victoria White
As part of the collaboration agreement, Symphogen is to receive $175 million upfront, in addition to potential future milestone payments and royalties...
Memory drug BPN14770 moves into Phase 1 safety trial
4 January 2016 | By Victoria White
BPN14770 may be a possible treatment for dementia and Alzheimer’s disease with less potential for side effects than rolipram...
Vertex and Genomics enter target pathway collaboration
4 January 2016 | By Victoria White
Vertex Pharmaceuticals is to use Genomic’s integrated database and state-of-the-art analysis tools to identify target therapeutic pathways...
Drug generates exciting results in metastatic breast cancer models
23 December 2015 | By Victoria White
A team at CSHL has announced preclinical data suggesting the promise of a novel drug directed against a novel target in malignant mammary tumours...
ARA 290 improves islet cell transplantation outcome in Type 1 diabetes
23 December 2015 | By Victoria White
ARA 290 is a first-in-class synthetic peptide designed to activate the innate repair mechanism in the setting of tissue injury...
Study identifies MDSCs as possible prostate cancer target
22 December 2015 | By Victoria White
MDSCs are immune cells that “expand” when faced with cancer, inflammation or infections, giving them the unique ability to suppress the body’s T-cell response to disease...
Enhancing proteasome activity may prevent dementia
22 December 2015 | By Victoria White
A study suggests that enhancing proteasome activity with drugs during the early stages of Alzheimer’s may prevent dementia and reduce damage to the brain...
IMI launches Calls to advance drug development in Ebola, Alzheimer’s and AMD
22 December 2015 | By Victoria White
The IMI has launched two Calls for proposals that will advance drug development in Ebola, childhood cancers, neurological disorders, and eye disease...
Mimetas awarded funding for organ-on-a-chip neurotoxicity models
22 December 2015 | By Victoria White
The funding is awarded in the context of the Neuratect CRACK IT Challenge to support development of better predictive, high-throughput, animal-free models for neurotoxicity of medicines and chemicals...
Bayer and CRISPR Therapeutics join forces for breakthrough therapies
21 December 2015 | By Victoria White
Bayer and CRISPR Therapeutics are to form the joint venture to discover, develop and commercialise new breakthrough therapeutics to cure blood disorders, blindness, and congenital heart disease...
Janssen and Bavarian Nordic team up for HPV infection vaccine
21 December 2015 | By Victoria White
Their goal is to develop a therapeutic vaccine which aims to intercept HPV infection-related disease, particularly in those who are diagnosed with HPV early, by enhancing the ability of the immune system to treat chronic infections and prevent progression to cancer...
Variant and L&F Research to advance development of VAR 200
18 December 2015 | By Victoria White
Variant says VAR 200 has potential for treating multiple indications associated with the damaging effects of cellular accumulation of cholesterol and lipids on the kidney, including focal segmental glomerulosclerosis...
Ligand Pharmaceuticals to acquire OMT for $178 million
18 December 2015 | By Victoria White
OMT has leading antibody drug discovery technology and is believed to be the only company in the world offering three transgenic animal platforms for license...
Duel homing agent could aid brain injury recovery
17 December 2015 | By Victoria White
When given to mice, the new ‘homing’ agent inactivated the complement system in the brain, reduced inflammation and aided recovery...