Genetics behind facial and skull changes in Down Syndrome mouse model
Progress in identifying the gene responsible for facial and skull changes in mouse model of Down Syndrome, made by UK researchers.
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Rhythmic brain activity helps maintain temporary memories
US researchers have discovered that rhythmic brain activity organises the neuronal pathways that maintain short-term memories.
T cells show immunity to a variety of bacteria
Australian scientists explored a group of bacterial pathogens that share a protein sequence which is recognised by human T cells.
Organ-on-a-chip device aids the study of thrombosis without animal models
Scientists from the University of Birmingham have developed an organ-on-a-chip-model to better understand the mechanisms of deep vein thrombosis.
Innovative treatment targets blood clots without increased bleeding risk
Safer and more effective blood thinners could be on the way following a ground-breaking discovery by US researchers, that have designed a new compound to target blood clots.
Researchers develop Raman imaging probes for detecting enzyme activities
Japanese researchers have developed activatable Raman probes based on 9CN-rhodol, offering a promising tool for detecting multiple enzyme activities in heterogeneous biological tissues. This new molecular design strategy allows for highly specific and sensitive detection of enzyme activities, offering potential applications in disease diagnosis and biological research.
Novel tool helps differentiate between cancerous and healthy cells for AML
Spanish scientists have developed a new method to identify between cancerous and healthy cells for cases of acute myeloid leukaemia (AML).
New treatment pathway for deadly pancreatic cancers
US scientists have used mouse models of pancreatic cancer to identify genes used by tumour cells to grow uncontrollably.
Inflammation ‘brake’ gene may impact kidney disease outcomes
Australian researchers uncover a gene that controls inflammation in kidney disease, which could pave the way for more precise disease diagnostics and personalised treatments.
Recombining drugs helps restore gene’s ability to signal for death of leukaemia cells
US researchers find combination of chloroquine and venetoclax promotes cancer cell death in mouse models with acute myeloid leukaemia (AML).
Cannabinoids used in worms can help regulate various body systems
US study suggest worms could be a good research model for understanding the endocannabinoid system—and possibly developing better drugs.
Brain cells found to transfer material to neurons in mice
Researchers have discovered that oligodendrocyte-lineage cells transfer cell material to neurons in a mouse brain. They have provided the first evidence of coordinated nuclear interaction between these cells and neurons.
Improved cognitive function in rats with serine racemase upregulation
US researchers have found that increasing the expression of the enzyme serine racemase in the prefrontal cortex of middle-aged rats can enhance cognitive function.
New digital map of sympathetic nervous system created
US researchers have created a digital map of sympathetic nervous system, in hope it will serve as a guide to treat cardiovascular conditions using bioelectronic devices
Resident T-cells key to salmonella immunity
According to US researchers, insights from mouse models of salmonella could lead to better vaccines and immunity.