Nanoparticles used to breach lung mucus barrier
4 August 2015 | By Victoria White
Researchers have used nanoparticles to breach the human airway mucus barrier of lung tissue - a finding that could lead to effective drug delivery systems...
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Global vaccine-development fund could save thousands of lives
4 August 2015 | By Victoria White
For vaccine development, financial barriers persist: pharma companies see high costs with limited market potential, and government support is lacking...
Neuroblastoma cells drain immune system’s batteries
3 August 2015 | By Victoria White
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for immune cells, leaving them too drained to fight the disease...
Prokarium gets funding from SynbiCITE to develop chlamydia vaccine
3 August 2015 | By Victoria White
Prokarium has received new funding from SynbiCITE that will enable it to complete preclinical development of an innovative chlamydia vaccine...
AZ and Isis Pharmaceuticals to discover antisense drugs
3 August 2015 | By Victoria White
AstraZeneca and Isis Pharmaceuticals are to collaborate to discover and develop antisense therapies for cardiovascular, metabolic and renal diseases...
Oxford Global’s Q&A session with Drug Discovery USA speaker Matthew Wagoner, a discovery safety specialist from AstraZeneca
31 July 2015 | By Oxford Global
In the run up to our 2nd Annual Drug Discovery USA Congress 2015, we spoke with Matthew Wagoner a discovery safety specialist from AstraZeneca, a confirmed speaker at the congress where he will talk about Bromodomain And ExtraTerminal (BET) Domain Inhibitors Induce A Loss Of Intestinal Stem Cells And Villous…
St Jude scientists identify new mechanism of p53-induced cell death
31 July 2015 | By Victoria White
Researchers have identified a new mechanism that the tumour suppressor protein p53 uses to trigger cell death via apoptosis...
Researchers resurrect ancient virus to improve gene therapy
31 July 2015 | By Victoria White
Researchers have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina...
Researchers uncover the signals that govern the fate of TFH cells
31 July 2015 | By Victoria White
Researchers identify a pair of master regulators that control the fate of follicular helper T (TFH) cells - a finding that could improve vaccine design...
Researchers design first artificial ribosome
30 July 2015 | By Victoria White
Researchers have engineered a tethered ribosome that may enable the production of new drugs and next-generation biomaterials...
IL-35 injections show promise as type 1 diabetes treatment
30 July 2015 | By Victoria White
Administration of IL-35 to mice with type 1 diabetes reverses or cures the disease by maintaining a normal blood glucose level and immune tolerance...
Inovio’s DNA-based monoclonal antibody (dMAb) protects against dengue
30 July 2015 | By Victoria White
Inovio’s DNA-based monoclonal antibody (dMAb) targeting dengue virus provided protection against a lethal dengue virus challenge in mice...
Sygnature Discovery delivers clinical candidate CORT125134 to Corcept
30 July 2015 | By Victoria White
Sygnature Discovery has delivered CORT125134, a glucocorticoid receptor antagonist in development for the treatment of Cushing’s syndrome, to Corcept...
Scientists successfully edit human T cells using CRISPR
29 July 2015 | By Victoria White
Scientists have precisely modifed human T cells using the CRISPR genome-editing system- a breakthrough that could lead to CRISPR/Cas9-based therapies...
Cystic fibrosis microbes able to survive on little to no oxygen
29 July 2015 | By Victoria White
CF microbes are able to survive in saliva and mucus that is chemically heterogeneous, including significant portions that are largely devoid of oxygen...