Study identifies microbe-gut signalling as potential new treatment for IBD
New research from Cincinnati Children’s Hospital Medical Center suggests blocking IL-22 and IL-1R could offer a promising IBD treatment.
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New drug provides optimism for individuals suffering from heart failure
A newly developed drug displays potential in treating both heart failure and the related sleep apnea.
Treating peanut allergies in mice with mRNA delivering nanoparticles
UCLA have developed technology using nanoparticles that deliver mRNA to liver cells, that could provide a platform to fight allergies.
New organoid emulates development of the human heart
The team are the first researchers in the world to successfully create an organoid containing both heart muscle cells and cells of the outer layer of the heart wall.
Artificial sweeteners weaken mice’s immune response to disease
New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.
New shape-shifting antibiotics could solve drug-resistant bacteria
US scientists have developed antibiotics that can “shape-shift”, which prevent bacteria from coming resistant against them.
Analysis of 33 tumour types identifies new immunotherapy targets
The researchers identified 1,068 transposable element-derived transcripts with the potential to produce tumour antigens that could serve as targets for new immunotherapies.
CBD compounds could reverse opioid overdoses
US researchers have studied (cannabidiol) CBD as a solution for opioid overdoses, instead of a popular opioid antidote.
Researchers develop screening model to evaluate potential cervical cancer drugs
Oregon State University researchers have developed a screening model for rapid testing of multiple drug compounds, using a 3D cellular platform.
Why do some immunotherapies fail to kill cancer?
Spreading cancer can halt natural pathway that should recruit killer T cells directly to where it has metastasised, US scientists report.
Mouse study at USC reveals why leukemic mutation varies
A mechanism linked to a genetic mutation could help identify patients who are at higher risk of developing leukaemia.
Therapeutic approach prevents resistance to chemo in colon and rectal cancer
Scientist and doctors from Spain have uncovered that oxaliplatin, a chemotherapy drug used to treat colon and rectal cancer, avoids the side effects this treatment can have on normal tumour cells, including potential chemotherapy resistance
Novel study suggests alternatives to aspirin with fewer side effects
The new findings could pave the way to safer aspirin alternatives and might also have implications for improving cancer immunotherapies.
Newly identified cell type could be key to preventing graft versus host disease
UW researchers at the Carbone Cancer Center have identified the cells that can cause graft versus host disease, the most common complication of bone marrow transplants.
Novel mRNA vaccines developed against Zika and HIV-1 viruses
US scientists have developed new mRNA vaccines for Zika virus and HIV-1 that produce a strong mother-to-child transmission of antibodies, in rabbits.