New self-powered drug delivery system
US researchers have invented a drug delivery technology that has implications for opioid epidemic, cancer treatment, rehabilitation care and more.
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Research shows lipid nanoparticles are highly effective in gene therapy
Lipid nanoparticles have been used to encapsulate CRISPR-Cas9 and deliver it to cells in mice, where it was highly effective at knocking down expression of a target protein.
Could long Covid be solved by autoantibodies?
Swiss researchers have found a new class of 'good autoantibodies', which are associated with a favourable course and lower risk of long-Covid.
Stopping immune cell leakage from tumours could improve skin cancer treatment
Results show the number of specialised immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumours.
New hydrogel stem cell treatment could repair injured brain tissue
The new ‘hybrid’ hydrogel allowed researchers to safely deliver stem cells to the site of a brain injury in mice.
Transplanted brain organoids show response to visual stimuli in adult rats
Researchers say that by looking at individual neurons, they were able to gain a deeper understanding of the integration of transplanted brain organoids.
Scientists create organoid to understand hearing loss
The ground-breaking study is an important step towards modelling cochlear function in a dish.
Researchers develop organoid models to study non-alcoholic fatty liver disease
The team used these models to show drug responses and established a CRISPR-screening platform to identify potential therapeutic targets for non-alcoholic fatty liver disease.
Weaponising SARS-CoV-2 spike protein against itself to prevent infection
By creating a drug that is based on part of the SARS-CoV-2 spike protein, US and Finnish researchers can block the virus from entering cells.
AI can help design drugs to treat opioid addiction
To help people with opioid addiction, US researchers are turning to AI to create and optimise potential new drugs.
Proteomics: dynamics of iron-sulphur cluster binding
Proteomic platform developed by US scientists affords a greater insight into the dynamics of iron-sulphur clusters delivery and binding.
The future for quality control of mRNA medications
Japanese researchers combine cutting edge mass spectrometry with software analysis to elucidate mRNA structure.
Usher syndrome: first nonhuman primate model
US researchers evaluate an experimental gene therapy in the first ever nonhuman primate model for Usher Syndrome.
Bacteria’s survival strategies against antibiotics
US researchers investigate how bacteria develop an antibiotic tolerance without mutations.
Therapeutic strategy using p53 induces cancer cell death
US researchers spotlight how p53, the most frequently mutated tumour suppressor gene, can be activated against cancer cells.