Usher syndrome: first nonhuman primate model
US researchers evaluate an experimental gene therapy in the first ever nonhuman primate model for Usher Syndrome.
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Bacteria’s survival strategies against antibiotics
US researchers investigate how bacteria develop an antibiotic tolerance without mutations.
Therapeutic strategy using p53 induces cancer cell death
US researchers spotlight how p53, the most frequently mutated tumour suppressor gene, can be activated against cancer cells.
Unlocking the secrets of Strep A virulence
Australian researchers have uncovered why some forms of Streptococcus A (Strep A) are associated with severe invasive infection.
Researchers discover small molecules that bind to SARS-CoV-2 spike proteins
The resulting compounds, which can bind to spike proteins from the original coronavirus, could serve as a starting point for developing broad-spectrum treatments for COVID-19.
What do cancer cells crave?
US researchers uncover the amino acid: arginine, that prompts genetic mutations in cancer cells.
New immunotherapy approach holds promise for ovarian cancer
A new approach using CAR T-cell therapy is suggested by Swedish researchers as an effective treatment for ovarian cancer.
Uncovering the first FDA-approved drug for Ebola virus infection
US scientists have outlined the structure and function of the first FDA approved drug for the Ebola virus.
What is the link between serotonin and heart valve disease?
US researchers found that serotonin impacts the mitral valve in the heart which can lead to heart valve disease.
Experimental antidepressant could also treat alcohol use disorder
A US pre-clinical study investigating the antidepressant: MAP4343, discovered it reduced alcohol intake in a mouse model of alcoholism.
Measles virus can develop mutations that cause fatal SSPE
Japanese researchers find a new mechanism for how the measles virus can cause a rare but fatal neurological disorder: subacute sclerosing panencephalitis (SSPE).
AI tools aid the discovery of super tight-binding antibodies
An AI strategy developed by US scientists could accelerate the development of new antibody drugs.
Can ketamine act as an antidepressant?
Chronic pain often leads to depression, which US researchers have potentially solved using a mechanism involved with ketamine.
Discovery of CAFs’ origin gives new direction for pancreatic cancer
US researchers discovered a type of cell involved it pancreatic cancer and sheds light on the origin of cancer-associated fibroblasts (CAFs).
Hypothalamus versus hippocampus: changes in the synaptic plasticity
Japanese scientists analyse the associative synaptic plasticity in the supramammillary nucleus–dentate gyrus pathways.