Lipid nanoparticle delivery of mRNA could lead to new ‘universal’ COVID-19 treatment
A study has shown that mRNA delivered via lipid nanoparticles blocks multiple variants of SARS-CoV-2 from entering cells in mice.
List view / Grid view
News
NIH awards $3.5 million grant for tuberculosis vaccine research
Texas Biomed and The Access to Advanced Health Institute have been granted $3.5 million to initiate tuberculosis vaccine research, which includes using genetically diverse animal models.
Target for possible osteoarthritis treatment found in RORβ protein
A new study has revealed that activating the RORβ protein could lead to a possible treatment and prevention for osteoarthritis.
New mitochondrial disease identified in identical twins
Unlike other mitochondrial diseases, a newly discovered form leads to hyperactive mitochondria, causing patients to have low body weight despite excessive food intake.
China approves IND application for Everest Medicines novel BTK inhibitor
The Chinese National Medical Products Administration has approved a Phase Ib study of Everest Medicines' EVER001, for potential treatment of glomerular diseases.
New drug discovery offers method to identify metabolic condition therapies
Drug-initiated activity metabolomics screening discovers the metabolite myristoylglycine, that converts white fat cells to brown fat cells.
Researchers develop robotic intracellular sensing system
An automated intracellular sensing system could provide an efficient approach to reveal the cellular characteristics of disease progression.
A new mechanism of drug resistance discovered for breast cancer
The scientists found the mechanism of drug resistance depends on activation of a protein called KDM1B which controls and regulates gene expression.
Decibel Therapeutics submits IND application for hearing loss gene therapy candidate
Decibel Therapeutics has submitted an IND application for a Phase I/II trial of DB-OTO, a gene therapy candidate to restore hearing.
New antibiotic could stop advance of resistant pathogens
Using computational screening, researchers have discovered an antibiotic called Dynobactin, that halts the advance of antibiotic-resistant bacteria.
Protein-based therapy shows promise for individuals with ALS
In a petri dish under an environmental condition reminiscent of ALS, the team found that the protein activates a unique pathway inside cells that increases survival and protects endothelial cells from toxic substances in the blood.
Silo Pharma initiates pre-IND package for ketamine to treat fibromyalgia
Silo Pharma says it is preparing a pre-IND package and meeting with the FDA for a topical formulation of ketamine to treat fibromyalgia.
CEPI awards $5.2m funding for Nipah virus vaccine research
A Boston University researcher has been granted funding for the development pre-clinical models to test potential Nipah virus vaccines.
Novel Zika vaccine shows promise in animal models
A potential Zika virus vaccine, developed by deleting part of the Zika genome that codes for the viral shell, was effective and safe in mice.
Study uncovers relationship between T cells and CD4
Researchers at the University of Arizona Health Sciences found that CD4 plays an active role in regulating T-cell receptor signalling.