Peptide delivered by nasal spray can reduce seizure activity
A novel peptide augments the brain’s natural mechanism to help prevent seizures and protect neurons in research models of both Alzheimer’s and epilepsy.
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Targeted cancer vaccines eliminate tumours and prevent recurrence in mice
Researchers have developed an mRNA-based cancer vaccine that is delivered directly into the lymphatic system for a more potent response.
New method enables efficient sample preparation for single-cell proteomics
Scientists develop a novel single-cell proteomics technique based on water droplet-in-oil digestion to enable efficient protein recovery.
New machine learning technique to accelerate the process of drug screening
Researchers have developed a machine learning method to quantitatively analyse and compare microscopy images of proteins.
Gene Lx9c11 helps mice survive virus infections
Researchers have discovered that “jumping gene” Lx9c11 has a profound effect on the immune system to virus infection.
Sound and electrical body stimulation could treat chronic pain
12 August 2022 | By
A new technique could relieve pain for individuals with various chronic and neurological conditions.
New needle-free nasal vaccine shows promise for COVID-19
Researchers have developed a needle-free mucosal bacteriophage (phage) T4-based COVID-19 vaccine is effective against SARS-CoV-2 infection.
Researchers find that CRISPR gene editing can give rise to cell toxicity and genomic instability
Using computational methods, researchers analysed the most popular CRISPR library designed for human cells and found 3,300 targeted spots that show strong toxic effects.
Novel streamlined screening method could discover new horizons in chemical reaction design
An in-silico reaction screening strategy could produce compounds potentially useful for novel drug development.
Scientists have identified novel molecular biomarkers in cells that spread triple-negative breast cancer
The researchers identified key molecular differences between triple-negative breast cancer cells that cling to an initial tumour and those that venture off to form distant tumours.
Novel insights into the genetic and molecular machinery that causes Alzheimer’s disease
Researchers have gained a clearer understanding of the genetic and molecular machinery in human microglia, findings that may provide insight into Alzheimer’s diseases development.
Nanoparticle vaccine protects against a range of COVID-19 variants
The vaccine attaches spike proteins from SARS-CoV-2 and seven other SARS-like betacoronaviruses to a protein nanoparticle structure, to induce the production of a broad spectrum of cross-reactive antibodies.
Newly identified compound reduces potency of Shiga toxin
Scientists have identified a molecule that can bind to a lethal subtype of the bacterial Shiga toxin, suppressing its deadly effects.
A new study has highlighted how an antibody strengthens bonds between cells
The monoclonal antibody 19A11 binds E-cadherin, a protein that helps cells stick together, especially in epithelial layers that line the skin, the gut and other organs.
Scientists uncover new therapeutic target for treating colorectal tumours
New study has demonstrated that mice deficient in dendritic cell immunoreceptor are resilient against colitis and colonic tumour growth.