New effective combination therapy for paediatric T-acute leukaemia
The combination of two drugs was more effective in eradicating leukaemia cells in zebrafish and human disease than using a single drug.
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A mathematical algorithm to network complex drug interactions
Researchers used mice to develop a mathematical algorithm of a heart attack.
Gene discovery indicates motor neurone diseases caused by abnormal lipid processing in cells
A new genetic discovery adds weight to a theory that motor neurone diseases are caused by abnormal lipid processing pathways inside brain cells.
Improving eye treatment delivery with microneedles
Scientists have developed self-plugging microneedles that could improve delivery of drugs into the eyeball.
New gene therapy improvement has massive potential
Scientists have developed a technology that can improve targeting specific organs and tissue types in gene therapy.
New combination therapy exploits ‘natural killer’ cells to destroy head and neck tumours
Scientists have identified a new treatment combination that is highly effective at suppressing the growth of head and neck tumours.
Global team aims to bring next generation CAR T-cell therapies to children with solid tumours
The Mark Foundation for Cancer Research awards ~$12 million to Cancer Grand Challenges Team to develop new immunotherapies for childhood solid tumours.
Novel microscopy technique to light the way towards new medicine
Researchers have developed a ground-breaking microscopy technique that allows proteins, DNA, and other tiny biological particles to be studied in their natural state in a completely new way.
Broadly neutralising antibodies could provide immunity against COVID-19 variants
A new study has highlighted two broadly neutralising antibodies show great promise to provide long-acting immunity against COVID-19 in immunocompromised populations.
New discovery could lead to treatment for cardiac hypertrophy
Scientists have identified an important new mechanism that causes the heart’s muscle to thicken which markedly increases the risk of irregular heart rhythms and cardiac hypertrophy.
Are we on our way to a one-time treatment for HIV?
Researchers have developed a new technology that could offer treatment for HIV infection through a single injection.
Mouse model of transgender men finds active testosterone worsens IVF results
The study found female mice currently receiving testosterone had fewer and less developed eggs retrieved. In contrast, discontinuing testosterone therapy in mice led to similar egg retrieval rates compared to the control group.
Immunity boosting treatment enhances CAR T-cell therapy for blood cancers
A new study in mice has shown blood cancer treatment with protein interleukin-7 revs up T-cell immunotherapy.
Using immunotherapy to prevent cancer metastases
Scientists have demonstrated how killer T cells used in immunotherapy to eliminate cancer cells can also destroy tumour lymphatic vessels, thus greatly reducing the risk of metastasis.
How do fast-growing bacteria resist antibiotics?
A new study has revealed how some fast-growing bacteria could be retreated with antibiotics.