New skin cell mechanism discovery could treat muscle-related diseases
Scientists have identified the mechanism behind the conversion of skin cells into immature muscle cells, which could lead to therapies preventing muscle degeneration.
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Mechanisms behind synapse degeneration in Alzheimer’s unveiled
Researchers have uncovered a signalling pathway associated with glutamatergic synapse degeneration in the brains of mice with Alzheimer’s.
Researchers discover glycan “gateway” that enables COVID-19 infection
A supercomputing method has revealed details of glycan “gates” on the SARS-CoV-2 Spike protein that open to allow virus entry and infection.
New study discovers how Parkinson’s-linked protein attacks mitochondria
Researchers have used fruit fly larvae to explore how alpha-synuclein impacts the mitochondria, advancing the study of Parkinson’s disease.
3D bioprinted blood vessel grown by Texas A&M engineers
A newly developed blood vessel model can mimic the states of health and disease, paving the way for cardiovascular drug advancements.
Genome-editing strategy may become novel Alzheimer’s treatment
Scientists have developed a new strategy using brain-wide genome-editing technology that reduced Alzheimer’s disease pathologies in mice.
Existing drug may improve immune response to leukaemia treatment
Researchers identified the inhibitor JQ1 as a potential drug to improve immune response to CAR T-cell therapies in leukaemia patients.
Quantifying method developed to improve neurodegeneration studies
Researchers have created a new method to quantify protein droplets involved in neurodegenerative diseases, enhancing the study of treatments.
CureVac and GSK COVID-19 vaccine shows promise in pre-clinical study
CureVac and GSK's second-generation mRNA COVID-19 vaccine candidate, CV2CoV, demonstrated improved immune response in a pre-clinical study.
New biomarkers may help prevent diabetes-related blindness
US researchers have identified new biomarkers that can detect early changes in the eye that can lead to diabetes-related blindness.
Enzyme discovery could fight against cancer and viral infections
A new study has identified a vital enzyme, known as APOBEC3A, that could lead to new treatments against cancers and viral infections.
Record-breaking 3D bioprinter could speed up drug development
Nanoengineers have developed a high-throughput bioprinter that 3D prints at record speed, potentially accelerating drug development.
New nanotechnology could combat colorectal cancer and melanoma
A nanotherapeutic delivery system displayed high efficacy against metastatic tumours in mice, potentially improving chemotherapy treatments.
Targeting interferon kappa could control psoriasis inflammation
Scientists found that changing interferon kappa levels altered the severity of psoriasis inflammation and cytokine production in mice.
TREM2 regulation to prevent neurodegeneration is possible, study shows
Scientists used a synthetic thyroid hormone in mice to regulate the TREM2 gene implicated in diseases such as Alzheimer’s and Parkinson’s.