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Slc4a4 restores normal brain function after ischemic stroke
Researchers have elucidated how Slc4a4 governs astrocyte-endothelial cell interaction in blood-brain barrier maintenance and repair.
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Baylor College of Medicine
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ERRγ controls parietal cells generation and maturation from stem cells
Researchers uncover a genetic pathway of parietal cell development, which will enable a better understanding of stomach conditions.
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How hematopoietic stem cells retain their regenerative potential
Researchers found that genetic depletion of cyclophilin A results in stem cells distinctively lacking intrinsically disordered proteins.
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A promising new treatment strategy for hepatoblastoma
A combination therapy of vincristine, irinotecan and panobinostat, tested in high-risk, relapsed or refractory HB spheroids, decreased tumour marker levels.
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Investigating the inflammatory myocardial microenvironment
By studying the molecular cell states within transplanted paediatric hearts, researchers have unlocked new treatment strategies.
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New technology to effectively regulate gene expression
A new strategy enables researchers to be more precise in the control of gene expression of a therapeutic protein.
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The promise of nanobodies to neutralise the human norovirus
A new discovery about the dynamic structure of norovirus particles has implications for vaccine development.
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New molecule disrupts pathways that promote cancer growth
Researchers have discovered a molecule that binds to a cancer cell protein, stopping growth of breast and ovarian tumours.
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New material engineered can repair severed nerves
Researchers designed the first magnetoelectric material that precisely stimulates neurons to treat nerve damage.
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New cancer diagnostics can predict chemotherapy response in triple negative breast cancer
US researchers innovate cancer diagnostics using Kinase Inhibitor Pulldown Assay, or KIPA, to search for proteins they could target to control tumour growth.
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Drug helps reduce bacterial antibiotic resistance
US researchers uncover a new drug that reduces the ability of bacteria to develop antibiotic resistance, prolonging the antibiotic effectiveness.
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A new way to visualise sensory neurons
US researchers have uncovered a novel method using a tool used to visualise ion channels in mechanosensory neurons.
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Targeted therapy for treatment-resistant breast cancer
US researchers have uncovered a potential target for treating breast cancer that is resistant to endocrine therapies because of a specific gene mutation.
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A promising oral drug delivery platform could replace injections with pills
The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.
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Protein Grb10 offers a potential new approach for treating obesity
The researchers found that the protein Grb10 promotes leptin activity in the brain, opening the possibility of developing Grb10-based new approaches to treat obesity.