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8 April 2020 | By Victoria Rees (Drug Target Review)
Sequencing almost 60,000 cells, researchers have found that certain cilia progenitor cells have gene transcripts for ACE2 and co-factor TMPRSS2, enabling COVID-19 infection.
6 February 2018 | By Drug Target Review
Scientists at the Berlin Institute of Health have discovered how mutations in a new disease gene CLCN2 cause the unusual inherited form of high blood pressure: Familial hyperaldosteronism type II.
13 December 2017 | By Alessandro Prigione, Carmen Lorenz, Gizem Inak
Mitochondrial DNA (mtDNA) mutations cause severe disorders that are untreatable and mostly affect the nervous system. The difficulty in funding therapies may also be explained by the lack of viable modelling systems...
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