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Novel DNA-free virus-like particles deliver gene-editing proteins to animal models
Researchers have developed a new drug delivery system using virus-like particles to successfully transport gene-editing proteins in pre-clinical studies.
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CRISPR activation screening: finding genes that interact with SARS-CoV-2
Dr Greg Neely, University of Sydney, explains how he and his team used pooled whole genome CRISPR activation screening to identify LRRC15 as a SARS-CoV-2 spike-interacting protein.
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New DNA-editing technique extends lifespan of mice with progeria
Researchers have used a novel DNA-editing method to convert one base pair to another, increasing the lifespan of mice with progeria.
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Next-generation diabetes prodrugs identified using novel screening platform
Researchers engineered the Disque Platform, a high-fidelity culture system, to enable them to screen drugs able to promote β cell proliferation.
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Human digestive tract database available for researchers
A team from MIT sequenced bacteria samples from the digestive system which can be accessed by researchers to use in the development of treatments.
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Gut microbiome identified as cause of IBD, study finds
A study has detailed the change in the gut microbiome, increasing the potential for new IBD therapies.
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Migraine study provides insight into the disease
By studying migraine patients researchers have identified over 40 significant genetic risk variants that predispose individuals to migraines...
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Human Cell Atlas data platform kicks off with support from CZI
The Chan Zuckerberg Initiative announced financial support for the Human Cell Atlas, which uses sequencing technology to redefine every cell in the body...
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Charles River demonstrates CRISPR/Cas9 genome engineering expertise
2 December 2016 | By Charles Rivers Laboratories
Charles River Laboratories has launched a full, end-to-end service offering of CRISPR/Cas9 genome engineering technology...
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TSRI study shows how Ebola adapted to better target human cells
3 November 2016 | By Niamh Louise Marriott, Digital Content Producer
A new study csuggests that Ebola virus gained a genetic mutation during the 2013 – 16 epidemic that appears to have helped it better target human cells...
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The impact of antibiotic exposure on the infant microbiome
15 June 2016 | By Victoria White, Digital Content Producer
An analysis of changes in the intestinal microbial population during the first three years of life has revealed some of the impacts of antibiotic exposure...
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Proteogenomic breast cancer study provides insight into potential therapeutic targets
26 May 2016 | By Victoria White, Digital Content Producer
Scientists have completed the first large-scale proteogenomic study of breast cancer, linking DNA mutations to protein signalling...
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Spotted gar could help advance biomedical research
7 March 2016 | By Victoria White
The genome of the spotted gar is so much like both zebrafish and humans that it can be used as a bridge species that could open a pathway to important advancements in biomedical research..
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Scientists significantly reduce errors in CRISPR-Cas9 genome editing system
1 December 2015 | By Victoria White
The team from the Broad Institute and the McGovern Institute for Brain Research found that mutations in three amino acids dramatically reduced “off-target” cuts...
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Team successfully performs surgery on a human genome
21 October 2015 | By Victoria White
The research team have changed how the genome is folded inside the nucleus. The advance may lead to new methods of understanding and overcoming genetic diseases...