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Cancer Research UK

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Developing the world’s first ovarian cancer prevention vaccine

7 October 2024 | By Drug Target Review

Cancer Research UK-funded researchers aim to identify targets for an ovarian cancer vaccine, which could prevent the disease at an early stage.

article

How MMR-deficient colorectal cancers regulate their growth

9 July 2024 | By Ellen Capon (Drug Target Review)

Understanding how MMR-deficient colorectal cancers drive tumour growth and avoid immune detection could pave the way for personalised cancer medicine.

news

Artificial sweeteners weaken mice’s immune response to disease

6 April 2023 | By Taylor Mixides (Drug Target Review)

New findings in mice using artificial sweeteners could result in new therapies to regulate the immune system in those with autoimmune diseases, potentially improving outcomes.

article

Five developments in oncology targets

30 July 2020 | By Hannah Balfour (Drug Target Review)

Drug Target Review explores some of the newest oncologic drug targets, including those for glioblastoma, lung cancer and breast cancer.

Immunotherapy - white blobs attacking a yellow cancer cell

news

Researchers find drug improves cancer immunotherapy in mice

3 March 2020 | By Victoria Rees (Drug Target Review)

A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.

news

Update on the development of new novel cancer immunotherapy

24 May 2019 | By Drug Target Review

The SCIB2 vaccine is to to be administered using new nanoparticle formulation in planned Phase 1/2 clinical trial.

news

Anticancer drug as an alternative to liver transplant

17 August 2018 | By Drug Target Review

Mouse models showed promise when an anticancer drug was used to treat liver failure, resulting in liver regeneration and preventing liver related death...

news

Inhibiting NAT10 provides therapeutic target for HGPS

30 April 2018 | By Dr Zara Kassam (Drug Target Review)

Scientists have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford progeria syndrome...

news

New class of drugs could help tackle treatment-resistant cancers

12 April 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies...

news

cDC1 cells could improve cancer immunotherapy

12 February 2018 | By Dr Zara Kassam (Drug Target Review)

Chemicals that attract specialised immune cells toward tumours could be used to develop better immunotherapies for cancer patients...

news

Scientists halt breast cancer spread

9 February 2018 | By Drug Target Review

Scientists have discovered that the amino acid asparagine is essential for breast cancer spread, and by restricting it, cancer cells stopped invading other parts of the body in mice.

news

DNA sequencing could open up new drug indications for rare cancers

8 September 2017 | By Dr Zara Kassam (Drug Target Review)

A network of hospitals have systematically collected biopsies from metastatic cancer patients in order to create a global database...

news

Anti-hormone therapy reduces recurrence of prostate cancer

5 September 2017 | By Dr Zara Kassam (Drug Target Review)

British scientists have investigated the impact of anti-hormone therapy on patients with prostate cancer...

news

New imaging technique may predict the of spread breast cancer

16 August 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers have developed a radioactive ‘tracer’ molecule to detect myeloid-derived suppressor cells’ accumulating in the lung in preparation for the arrival of breast cancer cells...

news

Novel immuno-oncology treatment for patients with advanced solid tumours

10 August 2017 | By Dr Zara Kassam (Drug Target Review)

An experimental immuno-oncology treatment will move into early phase clinical trials for patients with advanced solid tumours...

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