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New potential drug target is discovered for diabetes treatment
Researchers found heightened SCAN enzyme activity in humans and mice with diabetes results in excessive nitric oxide on insulin receptors.
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Case Western Reserve University
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A high-throughput macrodomain assay to identify coronavirus drugs
In the search for a rapid, easy way to identify drugs to fight SARS-CoV-2, researchers from across the US came together to develop and apply a high-throughput ADP-ribosylhydrolase assay, ADPr-Glo. Here, Dr Veronica Busa and Dr Anthony Leung from Johns Hopkins University describe the ADPr-Glo assay and how it can be…
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Novel CAR T-cell therapy for B-cell cancers shows promise in vivo
A new CAR T-cell therapy for B-cell cancers promises to reduce the antigen escape currently found in therapies that only target CD19.
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Novel protection pathway makes cells resistant to Ebola and coronavirus infection, report scientists
Researchers reveal that activating the MHC class II transactivator (CIITA) and CD74 genes protected cells against infection by Ebola and SARS-CoV-2.
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Imaging agents developed to better monitor growth of tumours
Imaging agents developed to better monitor the growth of tumours and generate new therapies...
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MRI agent distinguishes aggressive from slow-growing breast cancer
Researchers have tested a new MRI contrast agent that pinpoints breast cancers at early stages and differentiates between aggressive and slow-growing types...
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Small doses of anti-HIV drug efavirenz might treat Alzheimer’s
29 June 2016 | By Victoria White, Digital Content Producer
A study suggests efavirenz might be an effective therapy for stimulating cholesterol turnover from the brain and slowing or preventing Alzheimer's disease...